Research Grade Anti-Clostridium tetani tetX/Tetanus toxin (SAA0800) (JN990016)

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100ug
1mg

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Overview

Catalog No.	JN990016
Description	Anti-Clostridium tetani tetX/Tetanus toxin (SAA0800) (JN990016) is a research-grade recombinant antibody targeting tetX/Tetanus toxin. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Species reactivity	Clostridium tetani (strain Massachusetts / E88)
Applications	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Host species	Human
Isotype	IgG1
Clone ID	SAA0800
Expression system	Mammalian Cells
Clonality	Monoclonal
Target	tetX/Tetanus toxin
Endotoxin level	Please contact the lab for this information.
Purity	>95% purity as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	P04958
Form	Liquid
Storage buffer	0.01M PBS, pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
Alternate Names	TRN0010, TT0067
Background	Tetanus toxin (tetX) is a ~150 kDa protein. Tetanus toxin acts by inhibiting neurotransmitter release. It binds to peripheral neuronal synapses, is internalized and moves by retrograde transport up the axon into the spinal cord where it can move between postsynaptic and presynaptic neurons. It inhibits neurotransmitter release by acting as a zinc endopeptidase that catalyzes the hydrolysis of the '76-Gln-\|-Phe-77' bond of synaptobrevin-2.
Note	For research use only. Not suitable for clinical or therapeutic use.