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Research Grade Narnatumab (HC609016)

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  • 100ug
  • 1mg
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Overview
Catalog No.HC609016
Species reactivityHuman
ApplicationsELISA, Bioactivity: FACS, Functional assay, Research in vivo
Host speciesHuman
IsotypeIgG1-kappa
Expression systemMammalian Cells
ClonalityMonoclonal
TargetCD136, Macrophage-stimulating protein receptor, PTK8, MST1R, p185-Ron, RON, CDw136, MSP receptor, Protein-tyrosine kinase 8
Endotoxin levelPlease contact the lab for this information.
Purity>95% purity as determined by SDS-PAGE.
PurificationProtein A/G purified from cell culture supernatant.
AccessionQ04912
FormLiquid
Storage buffer0.01M PBS, pH 7.4.
Stability and StorageUse a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
Alternate NamesIMCRON-8, RON8, 1188275-92-4
BackgroundNarnatumab (IMC-RON8) is a neutralizing human monoclonal antibody that blocks RON binding to its ligand, macrophage-stimulating protein (MSP), with a Kd of 32 pM. Narnatumab can be used for the research of cancer.
NoteFor research use only. Not suitable for clinical or therapeutic use.
Images
  • SDS-PAGE

    SDS-PAGE for Research Grade Narnatumab.

  • Flow CytoMetry

    Flow-cytometry using PE anti-human CD136 antibody. SW480 cells were stained with an irrelevant antibody (Blue Histogram) or an PE anti-human CD136 monoclonal antibody (Catalog: HC609016, Yellow Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, and cells analysed on a NovoCyte Flow Cytometer.

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