

| Catalog No. | HV698031 |
|---|---|
| Description |
Recombinant Human FCRL5 Protein, C-Fc (HV698031) expressed in Mammalian Cells, spanning Met1-Arg844. Purity: >90% by SDS-PAGE.
Highlights
|
| Expression system | Mammalian Cells |
| Accession | Q96RD9 |
| Protein length | Met1-Arg844 |
| Applications | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| Species | Homo sapiens (Human) |
| Nature | Recombinant |
| Endotoxin level | Please contact with the lab for this information. |
| Purity | >90% as determined by SDS-PAGE. |
| Predicted molecular weight | 118.68 kDa |
| Form | Lyophilized |
| Storage buffer | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| Reconstitution | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Shipping | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Alternate Names | BXMAS1, CD307e, FCRH5, FCRL5, Fc receptor homolog 5, Fc receptor-like protein 5, FcR-like protein 5, FcRH5, FcRL5, IRTA2, Immune receptor translocation-associated protein 2 |
| Background | Fc receptor-like protein 5 is a ~106 kDa protein. Plays an important role in B-cell response to antigen that acts both as a negative or positive coreceptor. Inhibits B-cell receptor (BCR) signaling in the absence of CR2 stimulation but engagement with CR2 and the BCR lead to a superior calcium response compared to CR2 and BCR costimulation. May be involved in B-cell development and differentiation in peripheral lymphoid organs and may be useful markers of B-cell stages. May have an immunoregulatory role in marginal zone B-cells. May play a role in fertilization. 1. Franco, A. et al. (2018) International immunology 30, 569-578. PMID: 30107486 |
| Note | For research use only |




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