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Mouse TSPO Recombinant Protein (N-His) (MB258012)

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Overview
Catalog No.MB258012
Description
Recombinant Mouse TSPO Protein, N-His (MB258012) expressed in E. coli. Purity: >90% as determined by SDS-PAGE..
Highlights
  • E. coli Expression — High-yield, cost-effective production.
  • High Purity — >90% as determined by SDS-PAGE.
Expression systemE. coli
AccessionP50637
Protein lengthPro2-Glu169
ApplicationsELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
SpeciesMus musculus (Mouse)
Nature Recombinant
Endotoxin level Please contact with the lab for this information.
Purity >90% as determined by SDS-PAGE.
Form Lyophilized
Storage buffer Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Reconstitution Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate NamesBzrp, Mbr, Mitochondrial benzodiazepine receptor, PBR, PKBS, Peripheral-type benzodiazepine receptor, Translocator protein, Tspo
Background

Translocator protein is a ~18 kDa protein. Can bind protoporphyrin IX and may play a role in the transport of porphyrins and heme. Was initially identified as peripheral-type benzodiazepine receptor; can also bind isoquinoline carboxamides. Promotes the transport of cholesterol across mitochondrial membranes and may play a role in lipid metabolism, but its precise physiological role is controversial. According to some reports, it is not required for steroid hormone biosynthesis.

1. Li, H. et al. (1998) Endocrinology 139, 4991-7. PMID: 9832438
2. Taylor, JM. et al. (2014) Clinical science (London, England : 1979) 127, 603-13. PMID: 24814875
3. Morohaku, K. et al. (2014) Endocrinology 155, 89-97. PMID: 24174323
4. Tu, LN. et al. (2014) The Journal of biological chemistry 289, 27444-54. PMID: 24936060
Note For research use only
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
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Formula
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Stock Solution
C₁ (Stock Conc.)
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V₁ (Stock Vol.)
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