

| Catalog No. | HT477010 |
|---|---|
| Description |
InVivoMAb Anti-Human CD283/TLR3 Antibody (Iv0178) [Iv0178] (HT477010) is a mouse monoclonal antibody detecting TLR3 in Neutralization. Suitable for Human.
|
| Species reactivity | Human |
| Applications | Neutralization |
| Host species | Mouse |
| Isotype | IgG2a, kappa |
| Clone ID | Iv0178 |
| Clonality | Monoclonal |
| Target | TLR3, CD283, Toll-like receptor 3 |
| Endotoxin level | Please contact with the lab for this information. |
| Purity | >95% as determined by SDS-PAGE. |
| Purification | Protein A/G purified from cell culture supernatant. |
| Accession | O15455 |
| RRID | InVivoMAb Anti-Human CD283/TLR3 Antibody (Iv0178) (abinScience Cat# HT477010, RRID:AB_3727160) |
| Form | Liquid |
| Storage buffer | 0.01M PBS, pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. |
| Background | Toll-like receptor 3 (CD283/TLR3) is a ~103 kDa protein. Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR3 is a nucleotide-sensing TLR which is activated by double-stranded RNA, a sign of viral infection. Acts via the adapter TRIF/TICAM1, leading to NF-kappa-B activation, IRF3 nuclear translocation, cytokine secretion and the inflammatory response. |
| Note | For research use only. Not suitable for clinical or therapeutic use. |

SDS-PAGE for InVivoMAb Anti-Human CD283/TLR3 Antibody (Iv0178).




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