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InVivoMAb Anti-Mouse VTCN1/B7-H4 Antibody (Iv0257) (MV721010)

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InVivoMAb Anti-Mouse VTCN1/B7-H4 Antibody (Iv0257)

InVivoMAb Anti-Mouse VTCN1/B7-H4 Antibody (Iv0257)

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Spec:

100ug
1mg

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Overview
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Datasheet

Overview

Catalog No.	MV721010
Description	InVivoMAb Anti-Mouse VTCN1/B7-H4 Antibody (Iv0257) [Iv0257] (MV721010) is a mouse monoclonal antibody detecting V-set domain containing T-cell activation inhibitor 1 in ELISA, FCM, Neutralization. Suitable for Mouse. Highlights ●Multi-Application — Validated across multiple applications. ●Flow Cytometry — Validated for flow cytometry applications.
Species reactivity	Mouse
Applications	ELISA, FCM, Neutralization
Host species	Mouse
Isotype	IgG2a, kappa
Clone ID	Iv0257
Clonality	Monoclonal
Target	V-set domain containing T-cell activation inhibitor 1, B7 homolog 4, B7-H4, Immune costimulatory protein B7-H4, Protein B7S1, T cell costimulatory molecule B7x, Vtcn1, B7h4
Endotoxin level	Please contact with the lab for this information.
Purity	>95% as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	Q7TSP5
RRID	InVivoMAb Anti-Mouse VTCN1/B7-H4 Antibody (Iv0257) (abinScience Cat# MV721010, RRID:AB_3729559)
Form	Liquid
Storage buffer	0.01M PBS, pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Background	V-set domain containing T-cell activation inhibitor 1 (VTCN1/B7-H4) is a ~30 kDa protein. Negatively regulates T-cell-mediated immune response by inhibiting T-cell activation, proliferation, cytokine production and development of cytotoxicity. When expressed on the cell surface of tumor macrophages, plays an important role, together with regulatory T-cells (Treg), in the suppression of tumor-associated antigen-specific T-cell immunity. Involved in promoting epithelial cell transformation.
Note	For research use only. Not suitable for clinical or therapeutic use.

Images

Flow CytoMetry

Flow-cytometry using anti-human VTCN1 antibody. Untransfected cells (blue Histogram) and Transfected cells (Yellow Histogram) were stained with an anti-human VTCN1 monoclonal antibody (Catalog: MV721010) at a concentration of 5 µg/ml for 30 mins at RT. After washing, bound antibody was detected using a Goat Anti-Mouse IgG H&L Polyclonal Antibody, FITC (abinScience: MF690414) and cells analysed on a NovoCyte Flow Cytometer.

References

Datasheet

InVivoMAb Anti-Mouse VTCN1/B7-H4 Antibody (Iv0257).pdf

Formula

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InVivoMAb Anti-Mouse VTCN1/B7-H4 Antibody (Iv0257)