

| Catalog No. | VK496040 |
|---|---|
| Description |
InVivoMAb Anti-Influenza B virus NA/Neuraminidase Broad-Neutralizing Antibody (DA03E17) [DA03E17] (VK496040) is a human monoclonal antibody detecting EC:3.2.1.18 in ELISA, Neutralization. Suitable for Influenza B virus.
|
| Species reactivity | Influenza B virus |
| Applications | ELISA, Neutralization |
| Host species | Human |
| Isotype | IgG1, kappa |
| Clone ID | DA03E17 |
| Clonality | Monoclonal |
| Target | EC:3.2.1.18, NA, Neuraminidase |
| Endotoxin level | < 10 EU/mg |
| Purity | >95% as determined by SDS-PAGE. |
| Purification | Protein A/G purified from cell culture supernatant. |
| Accession | P03474 |
| Form | Liquid |
| Storage buffer | 0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. |
| Background | Neuraminidase (NA) is a ~51 kDa protein. Catalyzes the removal of terminal sialic acid residues from viral and cellular glycoconjugates. Cleaves off the terminal sialic acids on the glycosylated HA during virus budding to facilitate virus release. Additionally helps virus spread through the circulation by further removing sialic acids from the cell surface. These cleavages prevent self-aggregation and ensure the efficient spread of the progeny virus from cell to cell. Otherwise, infection would be limited to one round of replication. |
| Note | For research use only. |

SDS-PAGE for InVivoMAb Anti-Influenza B virus NA/Neuraminidase Broad-Neutralizing Antibody (DA03E17)
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