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InVivoMAb Anti-HCV E1 & E2 Complex Antibody (AR5A) (VK681080)

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InVivoMAb Anti-HCV E1 & E2 Complex Antibody (AR5A)

InVivoMAb Anti-HCV E1 & E2 Complex Antibody (AR5A)

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100ug
1mg

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Datasheet

Overview

Catalog No.	VK681080
Description	InVivoMAb Anti-HCV E1 & E2 Complex Antibody (AR5A) [AR5A] (VK681080) is a human monoclonal antibody detecting Genome polyprotein in ELISA, Neutralization.
Species reactivity	Hepatitis C virus genotype 1a (isolate H77) (HCV)
Applications	ELISA, Neutralization
Host species	Human
Isotype	IgG1
Clone ID	AR5A
Clonality	Monoclonal
Target	Genome polyprotein, Envelope glycoprotein E1, gp32, gp35, Envelope glycoprotein E2, NS1, gp68, gp70
Endotoxin level	Please contact with the lab for this information.
Purity	>95% as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	P27958
RRID	InVivoMAb Anti-HCV E1 & E2 Complex Antibody (AR5A) (abinScience Cat# VK681080, RRID:AB_3729573)
Form	Liquid
Storage buffer	0.01M PBS, pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Background	Genome polyprotein (E1 & E2 (gp35 & gp70)) is a ~327 kDa protein. Packages viral RNA to form a viral nucleocapsid, and promotes virion budding (Probable). Participates in the viral particle production as a result of its interaction with the non-structural protein 5A. Binds RNA and may function as a RNA chaperone to induce the RNA structural rearrangements taking place during virus replication. Modulates viral translation initiation by interacting with viral IRES and 40S ribosomal subunit. Affects various cell signaling pathways, host immunity and lipid metabolism (Probable). 1. Ivanyi-Nagy, R. et al. (2008) Nucleic acids research 36, 712-25. PMID: 18033802 2. Anjum, S. et al. (2013) Molecular medicine reports 8, 487-92. PMID: 23799612 3. Kittlesen, DJ. et al. (2000) The Journal of clinical investigation 106, 1239-49. PMID: 11086025 4. Waggoner, SN. et al. (2007) Journal of leukocyte biology 82, 1407-19. PMID: 17881511 5. Ruggieri, A. et al. (2003) Virus research 97, 103-10. PMID: 14602201
Note	For research use only. Not suitable for clinical or therapeutic use.

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SDS-PAGE

SDS-PAGE for InVivoMAb Anti-HCV E1 & E2 Complex Antibody (AR5A)

References

Datasheet

InVivoMAb Anti-HCV E1 & E2 Complex Antibody (AR5A).pdf

Formula

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InVivoMAb Anti-HCV E1 & E2 Complex Antibody (AR5A)