

| Catalog No. | VK422014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Species reactivity | Vesicular stomatitis Indiana virus (VSIV) | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Isotype | IgG | ||||||||
| Clonality | Polyclonal | ||||||||
| Immunogen | E. coli - derived recombinant VSIV G protein/Glycoprotein G (Lys17-Ser467). | ||||||||
| Target | G protein | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | P0C2X0 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Background | Glycoprotein G is a ~57 kDa protein. Attaches the virus to host LDL receptors, inducing clathrin-dependent endocytosis of the virion. In the endosome, the acidic pH induces conformational changes in the glycoprotein trimer, which trigger fusion between virus and endosomal membrane. 1. Nikolic, J. et al. (2018) Nature communications 9, 1029. PMID: 29531262 2. Roche, S. et al. (2006) Science (New York, N.Y.) 313, 187-91. PMID: 16840692 3. Roche, S. et al. (2007) Science (New York, N.Y.) 315, 843-8. PMID: 17289996 | ||||||||
| Note | For research use only. |

Western blot analysis was performed using anti-VSIV G protein/Glycoprotein G polyclonal antibody at 1ug/mL on recombinant VSIV G protein/Glycoprotein G (Catalog No. VK422012).




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