Anti-Human GSDMD Recombinant Antibody (SAA1652) (HX874013)

Name: Anti-Human GSDMD Recombinant Antibody (SAA1652)
Brand: abinScience
SKU: HX874013
Price: 196 USD
Availability: InStock

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1mg

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Overview
Images
References
Datasheet
SDS

Overview

Catalog No.

HX874013

Species reactivity

Human

Applications

ELISA

Host species

Mouse

Isotype

IgG2a, kappa

Clone ID

SAA1652

Clonality

Monoclonal

Target

GSDMD-CT, hGSDMD-NTD, Gasdermin domain-containing protein 1, Gasdermin-D, DFNA5L, GSDMD-NT, hGSDMD-CTD, GSDMDC1, GSDMD

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P57764

RRID

Anti-Human GSDMD Antibody (SAA1652) (abinScience Cat# HX874013, RRID:AB_3727413)

Form

Liquid

Storage buffer

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Background

Gasdermin-D (GSDMD) is a ~52 kDa protein. Precursor of a pore-forming protein that plays a key role in host defense against pathogen infection and danger signals. This form constitutes the precursor of the pore-forming protein: upon cleavage, the released N-terminal moiety (Gasdermin-D, N-terminal) binds to membranes and forms pores, triggering pyroptosis.

1. Shi, J. et al. (2015) Nature 526, 660-5. PMID: 26375003

2. Kayagaki, N. et al. (2015) Nature 526, 666-71. PMID: 26375259

3. Ding, J. et al. (2016) Nature 535, 111-6. PMID: 27281216

Note

For research use only.

Images

SDS-PAGE

SDS-PAGE for Anti-Human GSDMD Antibody (SAA1652)

References

Datasheet

Anti-Human GSDMD Recombinant Antibody (SAA1652).pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human GSDMD Recombinant Antibody (SAA1652) (HX874013)

Overview

Images

References

Datasheet

SDS

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