Anti-Human Di-acetylated histone H4/H4K5acK8ac Recombinant Antibody (2A7D9) (HX879023)

Name: Anti-Human Di-acetylated histone H4/H4K5acK8ac Recombinant Antibody (2A7D9)
Brand: abinScience
SKU: HX879023
Price: 126 USD
Availability: InStock

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Overview
Images
References
Datasheet
SDS

Overview

Catalog No.

HX879023

Species reactivity

Human

Applications

ELISA, WB

Host species

Mouse

Isotype

IgG2a, kappa

Clone ID

2A7D9

Clonality

Monoclonal

Target

Histone H4, H4C1, H4/A, H4FA, HIST1H4A, H4C2, H4/I, H4FI, HIST1H4B, H4C3, H4/G, H4FG, HIST1H4C, H4C4, H4/B, H4FB, HIST1H4D, H4C5, H4/J, H4FJ, HIST1H4E, H4C6, H4/C, H4FC, HIST1H4F, H4C8, H4/H, H4FH, HIST1H4H, H4C9, H4/M, H4FM, HIST1H4I, H4C11, H4/E, H4FE, HIST1H4J, H4C12, H4/D, H4FD, HIST1H4K, H4C13, H4/K, H4FK, HIST1H4L, H4C14, H4/N, H4F2, H4FN, HIST2H4, HIST2H4A, H4C15, H4/O, H4FO, HIST2H4B, H4C16, H4-16, HIST4H4

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

P62805

RRID

Anti-Human Di-acetylated histone H4/H4K5acK8ac Antibody (2A7D9) (abinScience Cat# HX879023, RRID:AB_3729521)

Form

Liquid

Storage buffer

0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Background

Histone H4 (Di-acetylated histone H4 Lys5/Lys8 (H4K5acK8ac)) is a ~11 kDa protein. Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

Note

For research use only.

Images

SDS-PAGE

SDS-PAGE for Anti-Human Di-acetylated histone H4/H4K5acK8ac Antibody (2A7D9)
Western blot

Western blot analysis was performed using anti-H4K5acK8ac monoclonal antibody at 1ug/mL on various samples.
Lane 1: HCT116 cell lysate