Anti-Human CD123/IL3RA Recombinant Antibody (SAA0045), APC (HB714137)

Name: Anti-Human CD123/IL3RA Recombinant Antibody (SAA0045), APC
Brand: abinScience
SKU: HB714137
Price: 290 USD
Availability: InStock

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Overview
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Datasheet
SDS

Overview

Catalog No.	HB714137
Species reactivity	Human
Applications	FCM, WB
Host species	Mouse
Isotype	IgG1, kappa
Clone ID	SAA0045
Conjugation	APC
Clonality	Monoclonal
Target	IL-3R subunit alpha, IL-3 receptor subunit alpha, CD123, Interleukin-3 receptor subunit alpha, IL3R, IL-3R-alpha, IL3RA, IL-3RA
Endotoxin level	Please contact with the lab for this information.
Associated products	Mouse IgG1, kappa Recombinant Isotype Control Antibody (MOPC-21), APC
Accession	P26951
Form	Liquid
Storage buffer	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Store at 4°C for 12 months. Protect from light. Do not freeze.
Background	Interleukin-3 receptor subunit alpha (CD123/IL-3Rα) is a ~43 kDa protein. Cell surface receptor for IL3 expressed on hematopoietic progenitor cells, monocytes and B-lymphocytes that controls the production and differentiation of hematopoietic progenitor cells into lineage-restricted cells. Ligand stimulation rapidly induces hetrodimerization with IL3RB, phosphorylation and enzyme activity of effector proteins such as JAK2 and PI3K that play a role in signaling cell proliferation and differentiation. Activation of JAK2 leads to STAT5-mediated transcriptional program. 1. Huang, S. et al. (1999) Stem cells (Dayton, Ohio) 17, 265-72. PMID: 10527461
Note	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.

Images

Flow Cytometry

Flow-cytometry using APC anti-Human CD123 antibody. KG-1 cells were stained with an irrelevant antibody (Green Histogram) or an APC anti-Human CD123 antibody monoclonal antibody (Catalog # HB714137 , Red Histogram) at a concentration of 5 µg/ml for 30 mins at RT. After washing, cells analysed on a NovoCyte Flow Cytometer.

References

Datasheet