Home > Products > Antibodies > Flow Cytometry (FACS) Antibodies

Anti-Human CD270/TNFRSF14 Antibody (36H12), APC (HV480137)

Datasheet Share product Copy info

Price(USD): $

Spec:

50T
100T

Number:

Contact us

Overview
Images
References
Datasheet

Overview

Catalog No.	HV480137
Description	Anti-Human CD270/TNFRSF14 Antibody (36H12), APC [36H12] (HV480137) is a mouse monoclonal antibody detecting TNFRSF14 in FCM. Suitable for Human. Highlights ●Flow Cytometry — Validated for flow cytometry applications. ●Fluorescent Label — Direct conjugate for streamlined workflows.
Species reactivity	Human
Applications	FCM
Host species	Mouse
Isotype	IgG1, kappa
Clone ID	36H12
Conjugation	APC
Clonality	Monoclonal
Target	HVEA, HVEM, Herpes virus entry mediator A, Tumor necrosis factor receptor superfamily member 14, Tumor necrosis factor receptor-like 2, HveA, TNFRSF14, CD270, TR2, Herpesvirus entry mediator A
Endotoxin level	Please contact with the lab for this information.
Accession	Q92956
Form	Liquid
Storage buffer	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Store at 4°C for 12 months. Protect from light. Do not freeze.
Background	Tumor necrosis factor receptor superfamily member 14 (CD270/TNFRSF14) is a ~30 kDa protein. Receptor for four distinct ligands: The TNF superfamily members TNFSF14/LIGHT and homotrimeric LTA/lymphotoxin-alpha and the immunoglobulin superfamily members BTLA and CD160, altogether defining a complex stimulatory and inhibitory signaling network. Signals via the TRAF2-TRAF3 E3 ligase pathway to promote immune cell survival and differentiation. Participates in bidirectional cell-cell contact signaling between antigen presenting cells and lymphocytes. In response to ligation of TNFSF14/LIGHT, delivers costimulatory signals to T cells, promoting cell proliferation and effector functions. Interacts with CD160 on NK cells, enhancing IFNG production and anti-tumor immune response. 1. Tamada, K. et al. (2000) Journal of immunology (Baltimore, Md. : 1950) 164, 4105-10. PMID: 10754304 2. Cai, G. et al. (2008) Nature immunology 9, 176-85. PMID: 18193050 3. Šedý, JR. et al. (2013) Journal of immunology (Baltimore, Md. : 1950) 191, 828-36. PMID: 23761635 4. Mauri, DN. et al. (1998) Immunity 8, 21-30. PMID: 9462508 5. Cheung, TC. et al. (2009) Journal of immunology (Baltimore, Md. : 1950) 183, 7286-96. PMID: 19915044 6. Hsu, H. et al. (1997) The Journal of biological chemistry 272, 13471-4. PMID: 9153189 7. Marsters, SA. et al. (1997) The Journal of biological chemistry 272, 14029-32. PMID: 9162022
Note	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.

Images

References

Datasheet

Anti-Human CD270/TNFRSF14 Antibody (36H12), APC.pdf

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

=

Concentration

×

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

×

V₁ (Stock Vol.)

=

Working Solution

C₂ (Working Conc.)

×

V₂ (Working Vol.)

Recommendation

Contact us for custom quotes, bulk requests and any other issues.

Mail: support@abinScience.com

Distributor list

Anti-Human CD270/TNFRSF14 Antibody (36H12), APC