

| Catalog No. | HV571237 |
|---|---|
| Description |
Anti-Human DLL4 Antibody (SAA0166), APC [SAA0166] (HV571237) is a human monoclonal antibody detecting DLL4 in FCM. Suitable for Human.
Highlights
|
| Species reactivity | Human |
| Applications | FCM |
| Host species | Human |
| Isotype | IgG1, kappa |
| Clone ID | SAA0166 |
| Conjugation | APC |
| Clonality | Monoclonal |
| Target | Delta-like protein 4, Drosophila Delta homolog 4, Delta4, DLL4 |
| Endotoxin level | Please contact with the lab for this information. |
| Accession | Q9NR61 |
| Form | Liquid |
| Storage buffer | 0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| Stability and Storage | Store at 4°C for 12 months. Protect from light. Do not freeze. |
| Background | Delta-like protein 4 (DLL4) is a ~74 kDa protein. Involved in the Notch signaling pathway as Notch ligand. Activates NOTCH1 and NOTCH4. Involved in angiogenesis; negatively regulates endothelial cell proliferation and migration and angiogenic sprouting. Essential for retinal progenitor proliferation. Required for suppressing rod fates in late retinal progenitors as well as for proper generation of other retinal cell types. 1. Yoneya, T. et al. (2001) Journal of biochemistry 129, 27-34. PMID: 11134954 2. Brütsch, R. et al. (2010) Circulation research 107, 592-601. PMID: 20616313 3. Del Barrio, MG. et al. (2007) Development (Cambridge, England) 134, 3427-36. PMID: 17728344 |
| Note | For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only. |




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