Anti-Mouse CD79b Antibody (HM79-16), PE (MW431127)

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Catalog No.	MW431127
Description	Anti-Mouse CD79b Antibody (HM79-16), PE [HM79-16] (MW431127) is a mouse monoclonal antibody detecting CD79b in FCM. Suitable for Mouse. Highlights ●Flow Cytometry — Validated for flow cytometry applications.
Species reactivity	Mouse
Applications	FCM
Host species	Mouse
Isotype	IgG2a, lambda
Clone ID	HM79-16
Conjugation	PE
Clonality	Monoclonal
Target	B-cell antigen receptor complex-associated protein beta chain, B-cell-specific glycoprotein B29, Ig-beta, Immunoglobulin-associated B29 protein, CD79b, Igb
Endotoxin level	Please contact with the lab for this information.
Accession	P15530
Form	Liquid
Storage buffer	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Store at 4°C for 12 months. Protect from light. Do not freeze.
Background	B-cell antigen receptor complex-associated protein beta chain (CD79B) is a ~25 kDa protein. Required in cooperation with CD79A for initiation of the signal transduction cascade activated by the B-cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Enhances phosphorylation of CD79A, possibly by recruiting kinases which phosphorylate CD79A or by recruiting proteins which bind to CD79A and protect it from dephosphorylation. CD79B is the therapeutic target of polatuzumab vedotin (Polivy).
Note	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.

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Anti-Mouse CD79b Antibody (HM79-16), PE.pdf

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Anti-Mouse CD79b Antibody (HM79-16), PE (MW431127)

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