

| Catalog No. | HY596010 |
|---|---|
| Description |
InVivoMAb Anti-Human CD49d/ITGA4 Antibody (Iv0201) [Iv0201] (HY596010) is a human monoclonal antibody detecting ITGA4 in ELISA, Neutralization. Suitable for Human.
|
| Species reactivity | Human |
| Applications | ELISA, Neutralization |
| Host species | Human |
| Isotype | IgG1, kappa |
| Clone ID | Iv0201 |
| Clonality | Monoclonal |
| Target | ITGA4, CD49d, CD49 antigen-like family member D, CD49D, VLA-4 subunit alpha, Integrin alpha-IV, Integrin alpha-4 |
| Endotoxin level | Please contact with the lab for this information. |
| Purity | >95% as determined by SDS-PAGE. |
| Purification | Protein A/G purified from cell culture supernatant. |
| Accession | P13612 |
| RRID | InVivoMAb Anti-Human CD49d/ITGA4 Antibody (Iv0201) (abinScience Cat# HY596010, RRID:AB_3727799) |
| Form | Liquid |
| Storage buffer | 0.01M PBS, pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term. |
| Background | Integrin alpha-4 (CD49d/ITGA4) is a ~114 kDa protein. Integrins alpha-4/beta-1 (VLA-4) and alpha-4/beta-7 are receptors for fibronectin. They recognize one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. They are also receptors for VCAM1. Integrin alpha-4/beta-1 recognizes the sequence Q-I-D-S in VCAM1. Integrin alpha-4/beta-7 is also a receptor for MADCAM1. 1. Fujita, M. et al. (2012) Journal of immunology (Baltimore, Md. : 1950) 189, 5809-19. PMID: 23125415 2. Saegusa, J. et al. (2008) The Journal of biological chemistry 283, 26107-15. PMID: 18635536 3. Fujita, M. et al. (2015) The Journal of biological chemistry 290, 259-71. PMID: 25398877 4. Morris, GE. et al. (2022) British journal of pharmacology 179, 4958-4973. PMID: 35802072 |
| Note | For research use only. Not suitable for clinical or therapeutic use. |

SDS-PAGE for InVivoMAb Anti-Human CD49d/ITGA4 Antibody (Iv0201).
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