Anti-Natalizumab ELISA Kit (AY596018)

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Overview

Catalog No.	AY596018
Description	Anti-Natalizumab ELISA Kit (AY596018) — Quantitative sandwich ELISA for Anti-Natalizumab. Sample: Plasma, Serum. Range: 156.25 - 10, 000 ng/mL. Highlights ●Sandwich Format — High specificity, reliable quantification. ●Ready-to-Use — Complete kit with pre-coated plates included.
Sample type	Plasma, Serum
Range	156.25 - 10, 000 ng/mL
Accession	P13612
Applications	ELISA
Detection method	Colorimetric
Assay type	Quantitative
Recovery	80-120%
Shipping	2-8 ℃
Stability and Storage	The stability of ELISA kit is determined by the loss rate of activity. The loss rate of this kit is less than 10% prior to the expiration date under appropriate storage condition.
Specifications	Natalizumab
Alternate Names	AN 100226, BG00002, 189261-10-7
Background	Integrin alpha-4 (Natalizumab) is a ~114 kDa protein. Integrins alpha-4/beta-1 (VLA-4) and alpha-4/beta-7 are receptors for fibronectin. They recognize one or more domains within the alternatively spliced CS-1 and CS-5 regions of fibronectin. They are also receptors for VCAM1. Integrin alpha-4/beta-1 recognizes the sequence Q-I-D-S in VCAM1. Integrin alpha-4/beta-7 is also a receptor for MADCAM1. 1. Fujita, M. et al. (2012) Journal of immunology (Baltimore, Md. : 1950) 189, 5809-19. PMID: 23125415 2. Saegusa, J. et al. (2008) The Journal of biological chemistry 283, 26107-15. PMID: 18635536 3. Fujita, M. et al. (2015) The Journal of biological chemistry 290, 259-71. PMID: 25398877 4. Morris, GE. et al. (2022) British journal of pharmacology 179, 4958-4973. PMID: 35802072
Note	For Research Use Only.