Anti-Measles virus/MeV F/Fusion Recombinant Antibody (mAb 77) (VK446023)

Name: Anti-Measles virus/MeV F/Fusion Recombinant Antibody (mAb 77)
Brand: abinScience
SKU: VK446023
Price: 370 USD
Availability: InStock

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100ug
1mg

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Overview

Catalog No.	VK446023
Species reactivity	Measles virus (MeV)
Applications	Neutralization, in vivo
Host species	Mouse
Isotype	IgG2a, kappa
Clone ID	mAb 77
Clonality	Monoclonal
Target	F/fusion protein
Endotoxin level	Please contact with the lab for this information.
Purity	>90% as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	P69353
RRID	Anti-Measles virus/MeV F/Fusion Antibody (mAb 77) (abinScience Cat# VK446023, RRID:AB_3730111)
Form	Liquid
Storage buffer	0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	Fusion glycoprotein F0, Fusion glycoprotein F2, Fusion glycoprotein F1, F
Background	Fusion glycoprotein F0 (fusion protein) is a ~59 kDa protein. Class I viral fusion protein. Under the current model, the protein has at least 3 conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state. During viral and plasma cell membrane fusion, the heptad repeat (HR) regions assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain. The formation of this structure appears to drive apposition and subsequent fusion of viral and plasma cell membranes. Directs fusion of viral and cellular membranes leading to delivery of the nucleocapsid into the cytoplasm.
Note	For research use only.