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Research Grade Anti-Human IL11RA Antibody (Hu16E12) (HC604026)

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Research Grade Anti-Human IL11RA Antibody (Hu16E12)

Research Grade Anti-Human IL11RA Antibody (Hu16E12)

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100ug
1mg

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Datasheet

Overview

Catalog No.	HC604026
Description	Anti-Human IL11RA Antibody (Hu16E12) (HC604026) is a research-grade recombinant antibody targeting IL-11RA. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
Species reactivity	Human
Applications	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
Host species	Human
Isotype	IgG4
Clone ID	Hu16E12
Expression system	Mammalian Cells
Clonality	Monoclonal
Target	IL-11RA, sIL-11R, Interleukin-11 receptor subunit alpha, sIL-11RA, IL11RA, IL-11R-alpha, IL-11R subunit alpha, IL-11 receptor subunit alpha, sIL11RA
Endotoxin level	Please contact the lab for this information.
Purity	>95% purity as determined by SDS-PAGE.
Purification	Protein A/G purified from cell culture supernatant.
Accession	Q14626
Form	Liquid
Storage buffer	0.01M PBS, pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
Background	Interleukin-11 receptor subunit alpha (IL11RA) is a ~45 kDa protein. Receptor for interleukin-11 (IL11). The receptor systems for IL6, LIF, OSM, CNTF, IL11 and CT1 can utilize IL6ST for initiating signal transmission. The IL11/IL11RA/IL6ST complex may be involved in the control of proliferation and/or differentiation of skeletogenic progenitor or other mesenchymal cells (Probable). Essential for the normal development of craniofacial bones and teeth. Restricts suture fusion and tooth number.
Note	For research use only. Not suitable for clinical or therapeutic use.

Images

SDS-PAGE

SDS-PAGE for Research Grade Anti-Human IL11RA Antibody (Hu16E12)

References

Datasheet

Research Grade Anti-Human IL11RA Antibody (Hu16E12).pdf

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Research Grade Anti-Human IL11RA Antibody (Hu16E12)