Research Grade Anti-Human IL11RA Antibody (X209) (HC604016)

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Price(USD): $

Spec:

100ug
1mg

Number:

Overview
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References
Datasheet

Overview

Catalog No.

HC604016

Description

Anti-Human IL11RA Antibody (X209) (HC604016) is a research-grade recombinant antibody targeting IL-11RA. Produced in mammalian cells with native-like glycosylation.

Highlights

●Research Grade — For PK/PD studies, assay development, and ADA research.
●Native Glycosylation — Mammalian expression ensures native-like patterns.

Species reactivity

Human

Applications

ELISA, WB, Bioactivity: FACS, Functional assay, Research in vivo

Host species

Human

Isotype

IgG4, kappa

Clone ID

X209

Expression system

Mammalian Cells

Clonality

Monoclonal

Target

IL-11RA, sIL-11R, Interleukin-11 receptor subunit alpha, sIL-11RA, IL11RA, IL-11R-alpha, IL-11R subunit alpha, IL-11 receptor subunit alpha, sIL11RA

Endotoxin level

Please contact the lab for this information.

Purity

>95% purity as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q14626

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.

Alternate Names

EnX209

Background

Interleukin-11 receptor subunit alpha (IL11RA) is a ~45 kDa protein. Receptor for interleukin-11 (IL11). The receptor systems for IL6, LIF, OSM, CNTF, IL11 and CT1 can utilize IL6ST for initiating signal transmission. The IL11/IL11RA/IL6ST complex may be involved in the control of proliferation and/or differentiation of skeletogenic progenitor or other mesenchymal cells (Probable). Essential for the normal development of craniofacial bones and teeth. Restricts suture fusion and tooth number.

Note

For research use only. Not suitable for clinical or therapeutic use.

Images

Bioactivity

Detects Recombinant Human IL11RA Protein, C-His (Cat No.: HC604011) in indirect ELISA.
SDS-PAGE

SDS-PAGE for Research Grade Anti-Human IL11RA Antibody (X209).
Western blot

Western blot analysis was performed using anti-IL11RA monoclonal antibody at 1μg/ml on various samples.
Lane 1: recombinant human IL11RA (Catalog No: HC604011)