

| Catalog No. | HA024022 |
|---|---|
| Description |
Recombinant Human PRAP1/uPA Protein, N-His (HA024022) expressed in E. coli, spanning Val21-Gln151. Purity: >90% by SDS-PAGE.
Highlights
|
| Expression system | E. coli |
| Accession | Q96NZ9 |
| Protein length | Val21-Gln151 |
| Applications | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| Species | Homo sapiens (Human) |
| Nature | Recombinant |
| Endotoxin level | Please contact with the lab for this information. |
| Purity | >90% as determined by SDS-PAGE. |
| Predicted molecular weight | 17.28 kDa |
| Form | Lyophilized |
| Storage buffer | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| Reconstitution | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Shipping | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Alternate Names | Epididymis tissue protein Li 178, PRAP1, Proline-rich acidic protein 1, UPA, Uterine-specific proline-rich acidic protein |
| Background | Proline-rich acidic protein 1 is a ~17 kDa protein. Lipid-binding protein which promotes lipid absorption by facilitating MTTP-mediated lipid transfer (mainly triglycerides and phospholipids) and MTTP-mediated apoB lipoprotein assembly and secretion. Protects the gastrointestinal epithelium from irradiation-induced apoptosis. May play an important role in maintaining normal growth homeostasis in epithelial cells. Involved in p53/TP53-dependent cell survival after DNA damage. May down-regulate the expression of MAD1L1 and exert a suppressive role in mitotic spindle assembly checkpoint in hepatocellular carcinomas. 1. Zhang, J. et al. (2003) Cancer research 63, 6658-65. PMID: 14583459 2. Huang, BH. et al. (2012) Cell death & disease 3, e442. PMID: 23235459 3. Sze, KM. et al. (2014) The Journal of pathology 233, 51-60. PMID: 24374861 |
| Note | For research use only |




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