Anti-Human PRAP1/uPA Antibody (SAA1888) (HA024013)

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100ug
1mg

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Overview
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Datasheet

Overview

Catalog No.

HA024013

Description

Anti-Human PRAP1/uPA Antibody (SAA1888) [SAA1888] (HA024013) is a mouse monoclonal antibody detecting PRAP1 in ELISA. Suitable for Human.

Species reactivity

Human

Applications

ELISA

Host species

Mouse

Isotype

IgG2a, kappa

Clone ID

SAA1888

Clonality

Monoclonal

Target

UPA, Proline-rich acidic protein 1, Epididymis tissue protein Li 178, Uterine-specific proline-rich acidic protein, PRAP1

Endotoxin level

Please contact with the lab for this information.

Purity

>95% as determined by SDS-PAGE.

Purification

Protein A/G purified from cell culture supernatant.

Accession

Q96NZ9

RRID

Anti-Human PRAP1/uPA Antibody (SAA1888) (abinScience Cat# HA024013, RRID:AB_3727652)

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:2000-1:20000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.

Background

Proline-rich acidic protein 1 (PRAP1/uPA) is a ~17 kDa protein. Lipid-binding protein which promotes lipid absorption by facilitating MTTP-mediated lipid transfer (mainly triglycerides and phospholipids) and MTTP-mediated apoB lipoprotein assembly and secretion. Protects the gastrointestinal epithelium from irradiation-induced apoptosis. May play an important role in maintaining normal growth homeostasis in epithelial cells. Involved in p53/TP53-dependent cell survival after DNA damage. May down-regulate the expression of MAD1L1 and exert a suppressive role in mitotic spindle assembly checkpoint in hepatocellular carcinomas.

1. Zhang, J. et al. (2003) Cancer research 63, 6658-65. PMID: 14583459

2. Huang, BH. et al. (2012) Cell death & disease 3, e442. PMID: 23235459

3. Sze, KM. et al. (2014) The Journal of pathology 233, 51-60. PMID: 24374861

Note

For research use only.

Images

SDS-PAGE

SDS-PAGE for Anti-Human PRAP1/uPA Antibody (SAA1888)

References

Datasheet

Anti-Human PRAP1/uPA Antibody (SAA1888).pdf

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Human PRAP1/uPA Antibody (SAA1888) (HA024013)

Overview

Images

References

Datasheet

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