

| Catalog No. | JN043016 | ||||
|---|---|---|---|---|---|
| Description |
Efungumab (JN043016) is a research-grade recombinant antibody targeting HSP90. Produced in mammalian cells with native-like glycosylation.
Highlights
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| Species reactivity | Candida albicans | ||||
| Applications | ELISA, Bioactivity: FACS, Functional assay, Research in vivo | ||||
| Host species | Human | ||||
| Isotype | scFv-heavy-kappa | ||||
| Expression system | Mammalian cells | ||||
| Clonality | Monoclonal | ||||
| Target | HSP90 | ||||
| Endotoxin level | Please contact the lab for this information. | ||||
| Purity | >95% purity as determined by SDS-PAGE. | ||||
| Purification | Protein A/G purified from cell culture supernatant. | ||||
| Accession | P46598 | ||||
| Form | Liquid | ||||
| Storage buffer | 0.01M PBS pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||
| Alternate Names | HSP90mab, Mycograb, 762260-74-2 | ||||
| Background | Heat shock protein 90 homolog (HSP90) is a ~80 kDa protein. Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. | ||||
| Note | For research use only. Not suitable for clinical or therapeutic use. |

SDS-PAGE for Research Grade Efungumab




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