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Anti-Human BMP10 Antibody (SAA0428), APC (HF791137)

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Overview

Catalog No.	HF791137
Description	Anti-Human BMP10 Antibody (SAA0428), APC [SAA0428] (HF791137) is a mouse monoclonal antibody detecting BMP10 in ELISA, FCM. Suitable for Human. Highlights ●Flow Cytometry — Validated for flow cytometry applications. ●Fluorescent Label — Direct conjugate for streamlined workflows.
Species reactivity	Human
Applications	ELISA, FCM
Host species	Mouse
Isotype	IgG2a, kappa
Clone ID	SAA0428
Conjugation	APC
Clonality	Monoclonal
Target	BMP-10, Bone morphogenetic protein 10, BMP10
Endotoxin level	Please contact with the lab for this information.
Accession	O95393
Form	Liquid
Storage buffer	0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Stability and Storage	Store at 4°C for 12 months. Protect from light. Do not freeze.
Background	Bone morphogenetic protein 10 (BMP10) is a ~48 kDa protein. Required for maintaining the proliferative activity of embryonic cardiomyocytes by preventing premature activation of the negative cell cycle regulator CDKN1C/p57KIP and maintaining the required expression levels of cardiogenic factors such as MEF2C and NKX2-5. Acts as a ligand for ACVRL1/ALK1, BMPR1A/ALK3 and BMPR1B/ALK6, leading to activation of SMAD1, SMAD5 and SMAD8 transcription factors. Inhibits endothelial cell migration and growth. May reduce cell migration and cell matrix adhesion in breast cancer cell lines.
Note	For flow cytometric staining, the suggested use of this reagent is 0.5 µg per million cells in 100 µL volume. It is recommended that the reagent be titrated for optimal performance for each application. For research use only.

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Datasheet

Anti-Human BMP10 Antibody (SAA0428), APC.pdf

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Anti-Human BMP10 Antibody (SAA0428), APC