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Anti-Human CXCL17/DMC/VCC1 Polyclonal Antibody (HV053014)

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Overview
Catalog No.HV053014
Description
Anti-Human CXCL17/DMC/VCC1 Polyclonal Antibody (HV053014) is a rabbit polyclonal antibody detecting CXCL17. Suitable for Human.
Species reactivityHuman
ApplicationsELISA, IHC, WB
Host speciesRabbit
IsotypeIgG
Clonality Polyclonal
Immunogen E. coli - derived recombinant Human CXCL17/DMC/VCC1 (Ser22-Leu119).
Target 4-Cys CXCL17, 6-Cys CXCL17, C-X-C motif chemokine 17, CXCL17, DMC, Dendritic cell and monocyte chemokine-like protein, VCC1, VEGF coregulated chemokine 1
Endotoxin level Please contact with the lab for this information.
Purification Purified by antigen affinity column.
Accession Q6UXB2
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Background

C-X-C motif chemokine 17 (CXCL17/DMC) is a ~13 kDa protein. Chemokine that acts as a chemoattractant for monocytes, macrophages and dendritic cells, and which is involved in immune regulation and lymphocyte trafficking. Activates the C-X-C chemokine receptor GPR25. Plays a key role in lymphocyte homing by activating the receptor GPR25 on lymphocytes, mediating lymphocyte recruitment into the respiratory, upper gastrointestinal, biliary and genito-urinary tracts. Plays a role in angiogenesis and possibly in the development of tumors. Acts as an anti-inflammatory in the stomach.

1. Pisabarro, MT. et al. (2006) Journal of immunology (Baltimore, Md. : 1950) 176, 2069-73. PMID: 16455961
2. Lee, WY. et al. (2013) American journal of physiology. Endocrinology and metabolism 304, E32-40. PMID: 23115081
3. Ocón, B. et al. (2024) Nature 635, 736-745. PMID: 39293486
4. Hu, WF. et al. (2025) The FEBS journal 292, 5998-6015. PMID: 40279398
5. Weinstein, EJ. et al. (2006) Biochemical and biophysical research communications 350, 74-81. PMID: 16989774
Note For research use only
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Datasheet
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
=
Concentration
×
Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
×
V₁ (Stock Vol.)
=
Working Solution
C₂ (Working Conc.)
×
V₂ (Working Vol.)
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Anti-Human CXCL17/DMC/VCC1 Polyclonal Antibody

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