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Anti-Kir2.2 K+ channel Recombinant Antibody (N124B/38) (HC427023)

Anti-Kir2.2 K+ channel Recombinant Antibody (N124B/38)
Anti-Kir2.2 K+ channel Recombinant Antibody (N124B/38)
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Overview
Catalog No.HC427023
Species reactivityRat
ApplicationsIHC, WB
Host speciesMouse
IsotypeIgG2a, kappa
Clone IDN124B/38
Clonality Monoclonal
Target Inward rectifier K(+) channel Kir2.2v, IRK-2, Inward rectifier K(+) channel Kir2.2, Potassium channel, inwardly rectifying subfamily J member 12, IRK2, KCNJN1, KCNJ12, ATP-sensitive inward rectifier potassium channel 12
Endotoxin level Please contact with the lab for this information.
Purity >95% as determined by SDS-PAGE.
Purification Protein A/G purified from cell culture supernatant.
Accession P52188
RRID

Anti-Kir2.2 K+ channel Antibody (N124B/38) (abinScience Cat# HC427023, RRID:AB_3728393)
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Form Liquid
Storage buffer 0.01M PBS pH 7.4

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information
Application Dilution
WB 1:500-1:2000
Stability and Storage Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C short term (1-2 weeks). Store at -20°C 12 months. Store at -80°C long term.
Background

ATP-sensitive inward rectifier potassium channel 12 (KCNJ12/Kir2.2 K+ channel) is a ~48 kDa protein. Inward rectifying potassium channel that probably participates in controlling the resting membrane potential in electrically excitable cells. It probably participates in establishing action potential waveform and excitability of neuronal and muscle tissues. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium.

Note For research use only.
Images
  • Anti-Kir2.2 K+ channel Recombinant Antibody (N124B/38)

    SDS-PAGE

    SDS-PAGE for Anti-Kir2.2 K+ channel Antibody (N124B/38)

References
Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.
Mass
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Concentration
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Volume
Molecular Weight *
g/mol
Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
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V₁ (Stock Vol.)
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Working Solution
C₂ (Working Conc.)
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V₂ (Working Vol.)
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