Anti-PIV5 F/Fusion glycoprotein F0 Polyclonal Antibody (VK583014)

Name: Anti-PIV5 F/Fusion glycoprotein F0 Polyclonal Antibody
Brand: abinScience
SKU: VK583014
Price: 168 USD
Availability: InStock

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Overview
Images
References
Datasheet
SDS

Overview

Catalog No.

VK583014

Description

Anti-PIV5 F/Fusion glycoprotein F0 Polyclonal Antibody (VK583014) is a rabbit polyclonal antibody detecting Fusion glycoprotein F0 in ELISA, IHC, WB.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Species reactivity

Parainfluenza virus 5 (PIV5)

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Parainfluenza virus 5 (PIV5) F/Fusion glycoprotein F0 (Ala126-Ser487).

Target

Fusion glycoprotein F0, Fusion glycoprotein F2, Fusion glycoprotein F1, F, Parainfluenza virus 5 (strain W3) (PIV5) (Simian virus 5)

Purification

Purified by antigen affinity column.

Accession

P04849

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Fusion glycoprotein F0 is a ~56 kDa protein. Class I viral fusion protein. Under the current model, the protein has at least 3 conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state. During viral and plasma cell membrane fusion, the heptad repeat (HR) regions assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain. The formation of this structure appears to drive apposition and subsequent fusion of viral and plasma cell membranes. Directs fusion of viral and cellular membranes leading to delivery of the nucleocapsid into the cytoplasm.

Note

For research use only.

Images

Western blot

Western blot analysis was performed using anti-F-PIV5 polyclonal antibody at 1ug/mL on various samples.
Lane 1: recombinant PIV5 F/Fusion glycoprotein F0 (Catalog No: VK583012)

References

Datasheet