Mouse NFKBIA Recombinant Protein (N-His) (MB155012)

Name: Mouse NFKBIA Recombinant Protein (N-His)
Brand: abinScience
SKU: MB155012
Price: 211 USD
Availability: InStock

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Overview

Catalog No.	MB155012
Description	Recombinant Mouse NFKBIA Protein, N-His (MB155012) expressed in E. coli, spanning Ala63-Asn276. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% purity verified by SDS-PAGE.
Expression system	E. coli
Accession	Q9Z1E3
Protein length	Ala63-Asn276
Applications	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
Species	Mus musculus (Mouse)
Nature	Recombinant
Endotoxin level	Please contact with the lab for this information.
Purity	>90% as determined by SDS-PAGE.
Predicted molecular weight	25.76 kDa
Form	Lyophilized
Storage buffer	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
Reconstitution	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
Shipping	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
Stability and Storage	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Alternate Names	I-kappa-B-alpha, IKBA, IkB-alpha, IkappaBalpha, MAD3, Major histocompatibility complex enhancer-binding protein MAD3, NF-kappa-B inhibitor alpha, NFKBI, NFKBIA
Background	NF-kappa-B inhibitor alpha is a ~35 kDa protein. Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL (RELA/p65 and NFKB1/p50) dimers in the cytoplasm by masking their nuclear localization signals. On cellular stimulation by immune and pro-inflammatory responses, becomes phosphorylated promoting ubiquitination and degradation, enabling the dimeric RELA to translocate to the nucleus and activate transcription. 1. Hatakeyama, S. et al. (1999) Proceedings of the National Academy of Sciences of the United States of America 96, 3859-63. PMID: 10097128 2. Spencer, E. et al. (1999) Genes & development 13, 284-94. PMID: 9990853 3. Brown, K. et al. (1995) Science (New York, N.Y.) 267, 1485-8. PMID: 7878466
Note	For research use only

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Datasheet

Mouse NFKBIA Recombinant Protein (N-His).pdf

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Mouse NFKBIA Recombinant Protein (N-His) (MB155012)

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