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A previously unobserved TREM2-positive macrophage subset in acne lesions

Science Immunology

Using a new single-cell analysis technology that identifies the types, as well as the location, of individual cells in a skin biopsy, the researchers found a previously unobserved type of macrophage – TREM2 – in hair follicles and around the sebaceous glands in acne lesions. They then identified the process by which TREM2 metabolizes lipids, digests bacteria and facilitates the skin infection. Until now, just two major types of macrophages – M1, which kills some types of bacteria, and M2, which acts as an anti-inflammatory – had been identified in acne.

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Catalog No.	Product Name	Description	Target
HV166053	Anti-Human TREM2 Antibody (SAA2090)	Anti-Human TREM2 Recombinant Antibody (SAA2090) (HV166053) is a human monoclonal antibody detecting TREM2 in ELISA. Suitable for Human. Highlights ●Affinity Purified — Minimal background and high purity for reliable results.	Triggering receptor expressed on myeloid cells 2, Triggering receptor expressed on monocytes 2, TREM-2, TREM2

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A previously unobserved TREM2-positive macrophage subset in acne lesions