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RORC+ dendritic cells in malignant ascites

Science Immunology

Multiomic profiling of malignant ascites from patients with gastric and esophageal cancer identifies a population of dendritic cells enriched in malignant ascites that express retinoic acid-related receptor C (RORC) and polymeric immunoglobulin receptor (PIGR). RORC+ DCs attenuated T cell effector responses.

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