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Dysregulated Klotho and FGF23 signaling aggravates vascular remodeling in age-related pulmonary hypertension

Paul-Lennard Perret, Jonathan H Kim, Annika Winkler, Christiane Ott, Willem Bintig, Teresa C Funk-Hilsdorf, Erik Asmus, Szandor Simmons, Laura Michalick, Philip D Solymosi, Petra Knaus, Catrin Herpich, Kristina Norman, Ursula Müller-Werdan, Vasile Foris, Gabor Kovacs, Makoto Kuro-O, Tilman Grune, Jakob Voelkl, Jana Grune, Wolfgang M Kuebler, Dysregulated Klotho and FGF23 signaling aggravates vascular remodeling in age-related pulmonary hypertension, Cardiovascular Research, 2026;, cvag048

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Monoclonal IgM antibodies mediate potent complement neutralization by targeting cell-derived epitopes on enveloped viruses

Kainulainen MH, Harmon JR, Bergeron É, Davies KA, LeBlanc ML, Clines C, Bentz ML, Montgomery JM, Spiropoulou CF.0.Monoclonal IgM antibodies mediate potent complement neutralization by targeting cell-derived epitopes on enveloped viruses. mBio0:e01709-25.https://doi.org/10.1128/mbio.01709-25IF: 4.7 Q1

Product recommends: Research Grade Eculizumab purchased from abinScience 2026-02-13
FungiGuard: identification of plant antifungal peptides with artificial intelligence

Li X, Fang Y, Wu Y, Yu X. FungiGuard: identification of plant antifungal peptides with artificial intelligence. Genome Biol. 2026 Feb 6. doi: 10.1186/s13059-026-03983-6. Epub ahead of print. PMID: 41645295.

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Migraine-induced cochlear injury triggers ZBP1-mediated PANoptosis via CGRP signaling

Xu, W., Zhai, N., Chen, J. et al. Migraine-induced cochlear injury triggers ZBP1-mediated PANoptosis via CGRP signaling. J Headache Pain 27, 61 (2026).

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Aged skin exacerbates experimental osteoarthritis via enhanced IL-36R signaling

Chen, D., Wang, C., Yang, C. et al. Aged skin exacerbates experimental osteoarthritis via enhanced IL-36R signaling. Nat Commun 17, 1695 (2026). https://doi.org/10.1038/s41467-026-68399-z

Product recommends: Research Grade Spesolimab purchased from abinScience 2026-01-14
Single-cell analysis reveals multi-faceted features of B cell development, together with age-associated B cell subpopulations

Yang X, Tang H, Lan C, et al. Single-cell analysis reveals multi-faceted features of B cell development, together with age-associated B cell subpopulations. Commun Biol. Published online January 10, 2026. doi:10.1038/s42003-026-09515-zIF: 5.1 Q1

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SAA restricts T cell mediated anti-tumor immunity by limiting antigen presentation in lung cancer

Huang M, Shi R, Xu C, et al. SAA restricts T cell mediated anti-tumor immunity by limiting antigen presentation in lung cancer. Front Immunol. 2025;16:1735479. Published 2025 Dec 19. doi:10.3389/fimmu.2025.1735479

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Recruiting ESCRT to single-chain heterotrimer peptide MHCI releases antigen-presenting vesicles that stimulate T cells selectively

Olson BA, Huey-Tubman KE, Mao Z, et al. Recruiting ESCRT to single-chain heterotrimer peptide MHCI releases antigen-presenting vesicles that stimulate T cells selectively. Proc Natl Acad Sci U S A. 2025;122(51):e2501046122. doi:10.1073/pnas.2501046122

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FOXA2 regulated by HDAC3-mediated deacetylation attenuates neuropathic pain by modulating microglial lipid metabolism and synaptic pruning dysregulation

Zeng, H., Wang, B., Huang, Z. et al. FOXA2 regulated by HDAC3-mediated deacetylation attenuates neuropathic pain by modulating microglial lipid metabolism and synaptic pruning dysregulation. J Neuroinflammation 22, 280 (2025).

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The eIF5A hypusination inhibitor GC7 improves tolerance of pancreatic beta cells to ischemia/reperfusion

Ouahmi H, Massa F, Cougnon M, et al. The eIF5A hypusination inhibitor GC7 improves tolerance of pancreatic beta cells to ischemia/reperfusion. Am J Physiol Cell Physiol. Published online November 19, 2025. doi:10.1152/ajpcell.00631.2025

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