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Circular RNA CLASP1 modulates the GLI1/SNAIL axis and enhances macrophage polarization in breast cancer

Zhou L, Liu M, Liu F, et al. Circular RNA CLASP1 modulates the GLI1/SNAIL axis and enhances macrophage polarization in breast cancer. Oncogene. 2025;44(49):4765-4780. doi:10.1038/s41388-025-03627-2

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Zero-loss semiconductor material-enhanced ultrasensitive metasurface biosensor for ultrahigh-affinity assessment of antibody-drug conjugates

Chen Y, Zhou R, Shu Y, Zhou H, Zheng W, Liu GL, Li Y, Huang L. Zero-loss semiconductor material-enhanced ultrasensitive metasurface biosensor for ultrahigh-affinity assessment of antibody-drug conjugates. Biosens Bioelectron. 2025 Nov 1;287:117740. doi: 10.1016/j.bios.2025.117740. Epub 2025 Jun 30. PMID: 40628022.

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Predominant mutated non-canonical tumor-specific antigens identified by proteogenomics demonstrate immunogenicity and tumor suppression in CRC

Xiang H, Guan X, Wei Y, et al. Predominant mutated non-canonical tumor-specific antigens identified by proteogenomics demonstrate immunogenicity and tumor suppression in CRC. Cell Genom. Published online November 13, 2025. doi:10.1016/j.xgen.2025.101062

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Gracillin Protects Liver Ischemia-Reperfusion Injury from Oxidative Stress-Induced Apoptosis

Shen Y, Shi R, Wang G, et al. Gracillin Protects Liver Ischemia-Reperfusion Injury from Oxidative Stress-Induced Apoptosis. Drug Des Devel Ther. 2025;19:10075-10090. Published 2025 Nov 12. doi:10.2147/DDDT.S479009

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ROR2-specific CAR T cells are effective against hematologic and solid tumors and well tolerated in mice

Weber J, Rade M, Michael J, et al. ROR2-specific CAR T cells are effective against hematologic and solid tumors and well tolerated in mice. Cell Rep Med. 2025;6(10):102400. doi:10.1016/j.xcrm.2025.102400

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Inhibition of eIF5A hypusination enhances antioxidant defense to prevent kidney Ischemia/Reperfusion injury

Marc Cougnon, Sébastien Giraud, Maria Materozzi, Elisa Allart, Isabelle Rubera, Claire Mackowiak, Gisèle Jarretou, Nadège Boildieu, Virginie Ameteau, Estelle Lemarié, Hajar Ouahmi, Nicolas Melis, Mallorie Poet, Christophe Duranton, Luc Pellerin, Laurent Counillon, Marina Shkreli, Michel Tauc, Thierry Hauet, Didier F. Pisani,Inhibition of eIF5A hypusination enhances antioxidant defense to prevent kidney Ischemia/Reperfusion injury,Redox Biology,

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High-throughput cell-free profiling of SARS-CoV-2 RBD variants enables rapid and quantitative in vitro affinity landscape mapping

Laura Grasemann, Jiami Han, Julia Tischler, Fatemeh Arefi, Maria Andrea Gonzales Castillo, Edward B Irvine, Ningning Chen, Sai T. Reddy, Sebastian J. Maerkl bioRxiv 2025.09.23.678000; doi: https://doi.org/10.1101/2025.09.23.678000

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HUMANIN produced by human efferocytic macrophages promotes the resolution of inflammation

Maraux, M., Vetter, M., Zuffo, L.D. et al. HUMANIN produced by human efferocytic macrophages promotes the resolution of inflammation. Cell Death Dis 16, 656 (2025). https://doi.org/10.1038/s41419-025-07909-1

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Structural and functional insights into the selective inhibition of mutant tau aggregation by purpurin and oleocanthal in frontotemporal dementia

Goud AC, Kozlov I, Skoupilová P, Malina L, Roy S, Das V. Structural and functional insights into the selective inhibition of mutant tau aggregation by purpurin and oleocanthal in frontotemporal dementia. Protein Sci. 2025;34(9):e70240. doi:10.1002/pro.70240

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Polymerization and flanking domains of the bactofilin BacA collectively regulate stalk formation in Asticcacaulis biprosthecum

Maxime Jacq,Paul D. Caccamo,Yves V. Brun Published: August 13, 2025 https://doi.org/10.1371/journal.pgen.1011542

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