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Zero-loss semiconductor material-enhanced ultrasensitive metasurface biosensor for ultrahigh-affinity assessment of antibody-drug conjugates

Chen Y, Zhou R, Shu Y, Zhou H, Zheng W, Liu GL, Li Y, Huang L. Zero-loss semiconductor material-enhanced ultrasensitive metasurface biosensor for ultrahigh-affinity assessment of antibody-drug conjugates. Biosens Bioelectron. 2025 Nov 1;287:117740. doi: 10.1016/j.bios.2025.117740. Epub 2025 Jun 30. PMID: 40628022.

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Predominant mutated non-canonical tumor-specific antigens identified by proteogenomics demonstrate immunogenicity and tumor suppression in CRC

Xiang H, Guan X, Wei Y, et al. Predominant mutated non-canonical tumor-specific antigens identified by proteogenomics demonstrate immunogenicity and tumor suppression in CRC. Cell Genom. Published online November 13, 2025. doi:10.1016/j.xgen.2025.101062

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Gracillin Protects Liver Ischemia-Reperfusion Injury from Oxidative Stress-Induced Apoptosis

Shen Y, Shi R, Wang G, et al. Gracillin Protects Liver Ischemia-Reperfusion Injury from Oxidative Stress-Induced Apoptosis. Drug Des Devel Ther. 2025;19:10075-10090. Published 2025 Nov 12. doi:10.2147/DDDT.S479009

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Galectin-9 activates the TLR4-NLRP3 inflammasome pathway and promotes tau pathology in Alzheimer’s disease

Xiaodi Guo, Guoxin Zhang, Qinyu Peng, Hui Liu, Keqiang Ye, Tingting Xiao, Chaoyang Liu, Xiangyan Zhang, Sheng Li, Hualong Wang, Jin Feng, Zhentao Zhang,Galectin-9 activates the TLR4-NLRP3 inflammasome pathway and promotes tau pathology in Alzheimer’s disease, Brain, Behavior, and Immunity,2025,

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Ligusticum chuanxiong Hort. Targets hsa-miR-10a-5p to Potentially Induce Apoptosis and Modulate Lipid Metabolism in Glioblastoma: A Natural-Product-Based Therapeutic Strategy

Cai, X.-X.; Zuo, H.-L.; Li, J.; Huang, H.-Y.; Li, L.-P.; Ni, J.; Wu, P.-S.; Xu, X.-Y.; Zhang, D.; Xie, Y.-Y.; et al. Ligusticum chuanxiong Hort. Targets hsa-miR-10a-5p to Potentially Induce Apoptosis and Modulate Lipid Metabolism in Glioblastoma: A Natural-Product-Based Therapeutic Strategy. Pharmaceuticals 2025, 18, 1553. https://doi.org/10.3390/ph18101553

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ROR2-specific CAR T cells are effective against hematologic and solid tumors and well tolerated in mice

Weber J, Rade M, Michael J, et al. ROR2-specific CAR T cells are effective against hematologic and solid tumors and well tolerated in mice. Cell Rep Med. 2025;6(10):102400. doi:10.1016/j.xcrm.2025.102400

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Inhibition of eIF5A hypusination enhances antioxidant defense to prevent kidney Ischemia/Reperfusion injury

Marc Cougnon, Sébastien Giraud, Maria Materozzi, Elisa Allart, Isabelle Rubera, Claire Mackowiak, Gisèle Jarretou, Nadège Boildieu, Virginie Ameteau, Estelle Lemarié, Hajar Ouahmi, Nicolas Melis, Mallorie Poet, Christophe Duranton, Luc Pellerin, Laurent Counillon, Marina Shkreli, Michel Tauc, Thierry Hauet, Didier F. Pisani,Inhibition of eIF5A hypusination enhances antioxidant defense to prevent kidney Ischemia/Reperfusion injury,Redox Biology,

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High-throughput cell-free profiling of SARS-CoV-2 RBD variants enables rapid and quantitative in vitro affinity landscape mapping

Laura Grasemann, Jiami Han, Julia Tischler, Fatemeh Arefi, Maria Andrea Gonzales Castillo, Edward B Irvine, Ningning Chen, Sai T. Reddy, Sebastian J. Maerkl bioRxiv 2025.09.23.678000; doi: https://doi.org/10.1101/2025.09.23.678000

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Microneedle-Delivered Multivalent MPXV DNA Vaccines Induce Promising Immunity Profiles and Cross-Protection in Mice

Wang Y, Cheng X, Huang B, et al. Microneedle-Delivered Multivalent MPXV DNA Vaccines Induce Promising Immunity Profiles and Cross-Protection in Mice. Immunology. Published online September 2, 2025. doi:10.1111/imm.70030

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Peptides Derived from α-Tubulin Induce Functional T Regulatory Cells

Fiyouzi, T.; Subiza, J.L.; Lafuente, E.M.; Reche, P.A. Peptides Derived from α-Tubulin Induce Functional T Regulatory Cells. Int. J. Mol. Sci. 2025, 26, 8356. https://doi.org/10.3390/ijms26178356

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