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Research Grade Iscalimab (HB782016)

데이터시트 제품 공유 정보 복사

Research Grade Iscalimab

Research Grade Iscalimab

Research Grade Iscalimab

Research Grade Iscalimab

가격(USD): $

사양:

100ug
1mg

수량:

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개요
이미지
참고 문헌
데이터시트

개요

카탈로그 번호	HB782016
설명	Iscalimab (HB782016) is a research-grade recombinant antibody targeting CD40. Produced in mammalian cells with native-like glycosylation. Highlights ●Research Grade — For PK/PD studies, assay development, and ADA research. ●Native Glycosylation — Mammalian expression ensures native-like patterns.
종 반응성	Human
응용 분야	ELISA, Bioactivity: FACS, Functional assay, Research in vivo
숙주 종	Human
이소타입	IgG1-kappa
발현 시스템	Mammalian Cells
클론성	Monoclonal
타겟	Tumor necrosis factor receptor superfamily member 5, B-cell surface antigen CD40, Bp50, CD40L receptor, TNFRSF5, CDw40, CD40
내독소 수준	Please contact the lab for this information.
순도	>95% purity as determined by SDS-PAGE.
정제	Protein A/G purified from cell culture supernatant.
등록번호	P25942
형태	Liquid
저장 완충액	0.01M PBS, pH 7.4. 데이터시트 인쇄본 또는 로트별 COA에 기재된 구체적인 완충액 정보를 참조하세요.
안정성 및 저장	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Store at 4°C for short-term storage (1-2 weeks). Store at -20°C for up to 12 months. For long-term storage, store at -80°C.
대체 이름	CFZ-533, NVP-CFZ533, OM11-62MF, 2031153-61-2
배경	Tumor necrosis factor receptor superfamily member 5 (CD40/TNFRSF5) is a ~30 kDa protein. Receptor for TNFSF5/CD40LG. Transduces TRAF6- and MAP3K8-mediated signals that activate ERK in macrophages and B cells, leading to induction of immunoglobulin secretion. 1. Takada, YK. et al. (2019) Journal of immunology (Baltimore, Md. : 1950) 203, 1383-1391. PMID: 31331973
참고사항	For research use only. Not suitable for clinical or therapeutic use.

이미지

Bioactivity

Detects Human CD40/TNFRSF5 in indirect ELISAs.
SDS-PAGE

SDS-PAGE for Research Grade Iscalimab.

참고 문헌

데이터시트

Research Grade Iscalimab.pdf

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

=

Concentration

×

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

×

V₁ (Stock Vol.)

=

Working Solution

C₂ (Working Conc.)

×

V₂ (Working Vol.)

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Research Grade Iscalimab