Anti-Mouse CD36 Polyclonal Antibody (MB030014)

Name: Anti-Mouse CD36 Polyclonal Antibody
Brand: abinScience
SKU: MB030014
Price: 96 USD
Availability: InStock

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Overview
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References
Datasheet
SDS

Overview

Catalog No.

MB030014

Species reactivity

Mouse, Rat

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Mouse CD36 (Lys56-Gly423).

Target

Cd36

Purification

Purified by antigen affinity column.

Accession

Q08857

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Platelet glycoprotein 4 (CD36) is a ~52 kDa protein. Multifunctional glycoprotein that acts as a receptor for a broad range of ligands. Ligands can be of proteinaceous nature like thrombospondin, fibronectin, collagen or amyloid-beta as well as of lipidic nature such as oxidized low-density lipoprotein (oxLDL), anionic phospholipids, long-chain fatty acids and bacterial diacylated lipopeptides. They are generally multivalent and can therefore engage multiple receptors simultaneously, the resulting formation of CD36 clusters initiates signal transduction and internalization of receptor-ligand complexes. The dependency on coreceptor signaling is strongly ligand specific. Cellular responses to these ligands are involved in angiogenesis, inflammatory response, fatty acid metabolism, taste and dietary fat processing in the intestine (Probable).

1. Endemann, G. et al. (1993) The Journal of biological chemistry 268, 11811-6. PMID: 7685021

2. Jimenez-Dalmaroni, MJ. et al. (2009) PloS one 4, e7411. PMID: 19847289

3. Stewart, CR. et al. (2010) Nature immunology 11, 155-61. PMID: 20037584

4. Heit, B. et al. (2013) Developmental cell 24, 372-83. PMID: 23395392

5. Wang, J. et al. (2019) Cell reports 26, 209-221.e5. PMID: 30605677

6. Hao, JW. et al. (2020) Nature communications 11, 4765. PMID: 32958780

7. Nassir, F. et al. (2007) The Journal of biological chemistry 282, 19493-501. PMID: 17507371

8. Masuda, D. et al. (2009) Journal of lipid research 50, 999-1011. PMID: 18753675

9. Tran, TT. et al. (2011) The Journal of biological chemistry 286, 25201-10. PMID: 21610069

10. Laugerette, F. et al. (2005) The Journal of clinical investigation 115, 3177-84. PMID: 16276419

Note

For research use only.

Images

Western blot

Western blot analysis was performed using anti-CD36 polyclonal antibody at 1µg/ml on various samples.
Lane 1: Mouse lung lysate
Lane 2: Mouse heart lysate

References

Datasheet

Anti-Mouse CD36 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-Mouse CD36 Polyclonal Antibody (MB030014)

Overview

Images

References

Datasheet

SDS

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