

| Catalog No. | MB782107 |
|---|---|
| Species reactivity | Mouse |
| Applications | in vivo NK cell depletion, FCMin vivo CD40 activation, in vitro B cell stimulation/activation |
| Host species | Rat |
| Clonality | Monoclonal |
| Isotype | IgG2a, kappa |
| Clone ID | FGK45 |
| Target | B-cell surface antigen CD40, Bp50, CD40, CD40L receptor, CDw40, TNFRSF5, Tumor necrosis factor receptor superfamily member 5 |
| Endotoxin level | < 10 EU/mg |
| Purity | >95% as determined by SDS-PAGE. |
| Purification | Protein A/G purified from cell culture supernatant. |
| Accession | P27512 |
| Form | Liquid |
| Storage buffer | 0.01M PBS pH 7.4. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| Background | Tumor necrosis factor receptor superfamily member 5 (CD40/TNFRSF5) is a ~32 kDa protein. Receptor for TNFSF5/CD40LG. Transduces TRAF6- and MAP3K8-mediated signals that activate ERK in macrophages and B cells, leading to induction of immunoglobulin secretion. 1. Eliopoulos, AG. et al. (2003) The EMBO journal 22, 3855-64. PMID: 12881420 |
| Note | For research use only. |

Detects CD40/TNFRSF5 in indirect ELISAs.




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