

| Catalog No. | VK673014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Species reactivity | Human metapneumovirus (HMPV) | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Isotype | IgG | ||||||||
| Clonality | Polyclonal | ||||||||
| Immunogen | E. coli - derived recombinant HMPV G/Major surface glycoprotein G (Asn52-Asn219). | ||||||||
| Target | Major surface glycoprotein G, Attachment glycoprotein G, Membrane-bound glycoprotein, mG, G | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | Q6WB94 | ||||||||
| RRID | Anti-HMPV G/Major surface glycoprotein G Polyclonal Antibody (abinScience Cat# VK673014, RRID:AB_3751825) |
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| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Background | Major surface glycoprotein G is a ~23 kDa protein. Attaches the virion to the host cell membrane by interacting with glycosaminoglycans, initiating the infection. Unlike other paramyxovirus attachment proteins, lacks both neuraminidase and hemagglutinating activities. In addition to its role in attachment, glycoprotein G interacts with host RIGI and inhibits RIGI-mediated signaling pathway in order to prevent the establishment of the antiviral state. | ||||||||
| Note | For research use only. |

Western blot analysis was performed using anti-HMPV G/Major surface glycoprotein G polyclonal antibody at 1ug/mL on recombinant HMPV G/Major surface glycoprotein G (Catalog No. VK673012).


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