In Vivo Antibodies

Q: How is an in vivo antibody different from standard lab grade?

In vivo products are azide-free, low endotoxin, sterile-filtered and aggregation-controlled, with carrier-free buffers and lot-level QC tailored to animal studies.

Q: Should I choose IgG or F(ab')2?

Use IgG for Fc effector functions (depletion/engagement); use F(ab')2 when avoiding FcγR interactions is important.

Q: Recommended endotoxin level?

Select low-endotoxin lots per protocol and record values from the lot-specific CoA; control endotoxin alongside dose and route.

Q: Can these be used in humans?

No. All products are for Research Use Only (RUO) and not intended for diagnostic or therapeutic use.

Q: What is InVivo Plus?

abinScience’s functional-grade specification with defined buffer, endotoxin and aggregation criteria; see the dedicated page for details.

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abinScience in vivo antibodies are functional-grade reagents optimized for animal studies—azide-free, low endotoxin, sterile-filtered and aggregation-tested. Available in blocking, depleting, and neutralizing formats with lot-specific CoA reporting purity, endotoxin (LAL), and sterility. Includes IgG, F(ab')2, and Fc-engineered options. RUO

Why Researchers Choose abinScience

Animal-Compatible Azide-free, carrier-free, sterile buffer

Low Endotoxin LAL-tested, ≤0.1 EU/μg typical

Aggregation Control SEC-HPLC/DLS verified

Flexible Formats IgG, F(ab')2, Fc variants

Lot-Specific QC CoA with endotoxin, purity, sterility

Shop by Function

Shop by Application

Selection & Handling Guide

Function: Select blocking, depleting, or neutralizing based on target and desired MoA.
Format: Choose IgG for Fc-mediated effects (ADCC/CDC); F(ab')2 to eliminate FcγR binding.
Dosing: Follow mg/kg guidelines from literature; common routes: i.p., i.v., s.c.
QC Review: Check lot CoA for endotoxin, purity, and sterility before use.
Controls: Always include matched isotype and vehicle controls.

Applications

Immunotherapy mechanism studies

Cell depletion in vivo

Cytokine blockade in disease models

Vaccine efficacy and immune modulation

Documents & QC

Lot-specific CoA: concentration, endotoxin, purity, sterility

Aggregation data (SEC-HPLC/DLS)

Recommended dosing and handling protocols

FAQs

How is an in vivo antibody different from standard lab grade?

In vivo products are azide-free, low endotoxin, sterile-filtered and aggregation-controlled, with carrier-free buffers and lot-level QC tailored to animal studies.

Should I choose IgG or F(ab')2?

Use IgG for Fc effector functions (depletion/engagement); use F(ab')2 when avoiding FcγR interactions is important.

Recommended endotoxin level?

Select low-endotoxin lots per protocol and record values from the lot-specific CoA; control endotoxin alongside dose and route.

Can these be used in humans?

No. All products are for Research Use Only (RUO) and not intended for diagnostic or therapeutic use.

What is InVivo Plus?

InVivo Plus is abinScience’s premium functional-grade specification with defined buffer, endotoxin and aggregation criteria; see the dedicated page for details.

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