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In Vivo Antibodies

abinScience in vivo antibodies are functional-grade reagents optimized for animal studies—azide-free, low endotoxin, sterile-filtered and aggregation-tested. Available in blocking, depleting, and neutralizing formats with lot-specific CoA reporting purity, endotoxin (LAL), and sterility. Includes IgG, F(ab')2, and Fc-engineered options. RUO

Why Researchers Choose abinScience

Animal-Compatible Azide-free, carrier-free, sterile buffer
Low Endotoxin LAL-tested, ≤0.1 EU/μg typical
Aggregation Control SEC-HPLC/DLS verified
Flexible Formats IgG, F(ab')2, Fc variants
Lot-Specific QC CoA with endotoxin, purity, sterility

Shop by Function

Shop by Application

Selection & Handling Guide

  1. Function: Select blocking, depleting, or neutralizing based on target and desired MoA.
  2. Format: Choose IgG for Fc-mediated effects (ADCC/CDC); F(ab')2 to eliminate FcγR binding.
  3. Dosing: Follow mg/kg guidelines from literature; common routes: i.p., i.v., s.c.
  4. QC Review: Check lot CoA for endotoxin, purity, and sterility before use.
  5. Controls: Always include matched isotype and vehicle controls.

Applications

Immunotherapy mechanism studies
Cell depletion in vivo
Cytokine blockade in disease models
Vaccine efficacy and immune modulation

Documents & QC

Lot-specific CoA: concentration, endotoxin, purity, sterility
Aggregation data (SEC-HPLC/DLS)
Recommended dosing and handling protocols

FAQs

How is an in vivo antibody different from standard lab grade?

In vivo products are azide-free, low endotoxin, sterile-filtered and aggregation-controlled, with carrier-free buffers and lot-level QC tailored to animal studies.

Should I choose IgG or F(ab')2?

Use IgG for Fc effector functions (depletion/engagement); use F(ab')2 when avoiding FcγR interactions is important.

Recommended endotoxin level?

Select low-endotoxin lots per protocol and record values from the lot-specific CoA; control endotoxin alongside dose and route.

Can these be used in humans?

No. All products are for Research Use Only (RUO) and not intended for diagnostic or therapeutic use.

What is InVivo Plus?

InVivo Plus is abinScience’s premium functional-grade specification with defined buffer, endotoxin and aggregation criteria; see the dedicated page for details.

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    Antibodies (510)
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    Capsid protein VP1/VP3/VP4 (2)
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    shiga toxin type 1B/stx1B (1)
    APOE (1)
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    ProteinUL128 & UL131A (1)
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    IL11RA (2)
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    CCL24/Eotaxin-2/MPIF-2 (1)
    TPSAB1/Tryptase-1 (1)
    CD276/B7-H3 & CD3E (1)
    gH/gL Complexes (2)
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    env/Envpolyprotein (1)
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    env/Env polyprotein (4)
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    CDH11 (1)
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    CD37/TSPAN26 (1)
    Flt3 ligand/FLT3LG (1)
    Procapsid [(VP0/1/3) 5] 12 (2)
    F/Fusion glycoprotein F0 (8)
    ADAMTS5 (2)
    TGFA/TGF-alpha (1)
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    mature virion in complex (5)
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    gB/Envelope glycoprotein B (8)
    HLA-A*11:01 (1)
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    CA9 (1)
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    gD/Envelope glycoprotein D (2)
    F12/Coagulationfactor XII (1)
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    CD79B & CD3E (1)
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    GP1 glycoprotein (2)
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    iga/IgA1 protease (1)
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    E1 & E2 (gp35 & gp70) (3)
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    Fusion glycoprotein F0 (4)
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    Glycoprotein G (6)
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    Human parvovirus B19 (HPV B19) (3)
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    Cat (1)
    Human astrovirus-8 (HAtVs) (1)
    Dog (11)
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    Human papillomavirus 6 (HPV6) (1)
    Orthohantavirus puumalaense (PUUV) (1)
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    Machupo virus (MACV) (1)
    Human hepatitis A virus (HHAV) (1)
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    Brazilian scorpion (1)
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    Coxsackievirus B1 (CBV1) (3)
    Severe acute respiratory syndrome coronavirus (SARS-CoV) (3)
    Campylobacter jejuni subsp. (1)
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    Cell Deplete (1)
    Functional assay (2)
    in vivo study (4)
    ICC (1)
    in vivo blocking of PD-1/PD-L signaling (2)
  • Reactivity
    0 selected
    Mouse (12)
    Puumala virus (1)
    Human (16)
    Coxsackievirus B1 (CVB1) (3)
    Influenza B virus (1)
    Chikungunya virus (1)
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    Mouse (161)
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    Human (319)
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  • Clonality
    0 selected
    Monoclonal (510)
  • Conjugate
    0 selected
    Unconjugated (510)

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