Please ensure Javascript is enabled for purposes of website accessibility
Contact us Contact Us
EN
Home > Products > Antibodies > Invivo Antibodies

In Vivo Antibodies

abinScience in vivo antibodies are functional-grade reagents optimized for animal studies—azide-free, low endotoxin, sterile-filtered and aggregation-tested. Available in blocking, depleting, and neutralizing formats with lot-specific CoA reporting purity, endotoxin (LAL), and sterility. Includes IgG, F(ab')2, and Fc-engineered options. RUO

Why Researchers Choose abinScience

Animal-Compatible Azide-free, carrier-free, sterile buffer
Low Endotoxin LAL-tested, ≤0.1 EU/μg typical
Aggregation Control SEC-HPLC/DLS verified
Flexible Formats IgG, F(ab')2, Fc variants
Lot-Specific QC CoA with endotoxin, purity, sterility

Shop by Function

Shop by Application

Selection & Handling Guide

  1. Function: Select blocking, depleting, or neutralizing based on target and desired MoA.
  2. Format: Choose IgG for Fc-mediated effects (ADCC/CDC); F(ab')2 to eliminate FcγR binding.
  3. Dosing: Follow mg/kg guidelines from literature; common routes: i.p., i.v., s.c.
  4. QC Review: Check lot CoA for endotoxin, purity, and sterility before use.
  5. Controls: Always include matched isotype and vehicle controls.

Applications

Immunotherapy mechanism studies
Cell depletion in vivo
Cytokine blockade in disease models
Vaccine efficacy and immune modulation

Documents & QC

Lot-specific CoA: concentration, endotoxin, purity, sterility
Aggregation data (SEC-HPLC/DLS)
Recommended dosing and handling protocols

FAQs

How is an in vivo antibody different from standard lab grade?

In vivo products are azide-free, low endotoxin, sterile-filtered and aggregation-controlled, with carrier-free buffers and lot-level QC tailored to animal studies.

Should I choose IgG or F(ab')2?

Use IgG for Fc effector functions (depletion/engagement); use F(ab')2 when avoiding FcγR interactions is important.

Recommended endotoxin level?

Select low-endotoxin lots per protocol and record values from the lot-specific CoA; control endotoxin alongside dose and route.

Can these be used in humans?

No. All products are for Research Use Only (RUO) and not intended for diagnostic or therapeutic use.

What is InVivo Plus?

InVivo Plus is abinScience’s premium functional-grade specification with defined buffer, endotoxin and aggregation criteria; see the dedicated page for details.

Options+
Options
Confirm
  • Product types
    0 selected
    Antibodies (510)
  • Target
    0 selected
    VP1/Coatprotein VP1 (2)
    CD307e/FCRL5 (1)
    PRLR (1)
    TCRαβ/alpha-beta TCR (1)
    ANGPTL4 (2)
    shiga toxin type 2/stx2B (1)
    GP/Glycoprotein (5)
    CD122/IL2RB (1)
    CD340/ERBB2 (1)
    PDGFC (1)
    Major capsid protein L1 (3)
    LGR5/GPR49 (1)
    EGFRvIII & CD3E (1)
    F8/Coagulation factor VIII (7)
    wlaB/pglK (1)
    CD20/MS4A1 & CD3E (1)
    IL8/CXCL8 (1)
    CLDN3/Claudin-3 (1)
    FGF21 (1)
    CCL14/NCC-2 (1)
    APOE2/3/4 (1)
    IL10 (1)
    Outer capsid protein VP4 (2)
    IL18/IL1F4 (1)
    BTN3A (1)
    IL17F (1)
    GDF15/MIC1 (1)
    Toxin B/tcdB (1)
    TGM2 (1)
    EGFRvIII-specific/EGFR variant III (2)
    TSLP (1)
    SAA (2)
    Protease/PR (1)
    CXCL1/NAP-3/GRO-alpha (1)
    CCL2/MCP-1 (1)
    MUC5AC (1)
    ROR1/NTRKR1 (1)
    Fluorescein & CD274/PD-L1 (1)
    ARG1/Arginase-1 (2)
    OPN/SPP1 (1)
    Fc Block (1)
    CD172a/SIRPA (3)
    FAP & CD3E (1)
    Glycoprotein C/Gc (2)
    LTA/TNF-beta (1)
    LAMP5 (1)
    PTP4A3/PRL3 (1)
    gp140/Env Trimer (2)
    CD340/ERBB2 & CD3E (2)
    CD279/PD-1 & CD274/PD-L1 (1)
    RBP2b (1)
    TREML1/TLT1 (1)
    MSLN/Mesothelin (1)
    TSG101 (2)
    CD4 (1)
    ERVW-1/HERV-W-Env (1)
    SFRP1 (1)
    CD110/TPOR (2)
    VLP (1)
    CD120b/TNFR2 (1)
    BAG3 (1)
    SNCA/Alpha-synuclein (5)
    ACE2 (2)
    IL13 (1)
    Blood group Hantigen/Globo H (3)
    FAP/FAPalpha (1)
    Pvs25 (1)
    Mature virion in Complex [(VP0/1/3)5]12 (2)
    CDH17/Cadherin-17 (1)
    entB/SEB (1)
    CD335/NCR1/NKp46 (1)
    IL22 (1)
    gB/BALF4 (2)
    EGFL7 (1)
    Capsid protein VP1 (2)
    HBsAg (5)
    Fusion glycoprotein/F Trimer (1)
    CD3E (2)
    TSHR/LGR3 (2)
    PF45/48 (2)
    IL6R (1)
    IL9 (1)
    Outer capsid glycoprotein VP7 (1)
    CD115/CSF1R (1)
    PSCA (1)
    CXCL9/MIG (1)
    IFNB1/IFN-beta (1)
    Envelope protein E (7)
    Alpha-toxin/hly (1)
    Fluorescein & CD47/MER6 (1)
    botA/BoNT (2)
    VTCN1/B7-H4 (1)
    IL2 (1)
    HGF (1)
    TRP-1 & CD134/OX40 (1)
    CSF2/GM-CSF (1)
    CD19 & CD3E (1)
    CD114/G-CSFR (1)
    IGF1 (2)
    GREM1/DAND2 (1)
    CFD (1)
    Capsid protein VP1/VP3/VP4 (2)
    sLea/CA19-9 (1)
    shiga toxin type 1B/stx1B (1)
    IL5 (1)
    NGF/Beta-NGF (2)
    CD279/PD-1 & CD47/MER6 (1)
    S2 Protein (1)
    IL1B/IL1F2 (1)
    CSF1/M-CSF (1)
    IFNAR1 (1)
    STAT3 (1)
    GDF11/BMP11 (1)
    S/Spike glycoprotein (1)
    VSIG4/CRIg (1)
    IL31RA (1)
    IFNG/IFN-gamma (2)
    BDNF (1)
    RAGE/AGER (3)
    gE/Envelope glycoprotein E (1)
    HA/Hemagglutinin (7)
    cyaA/Cyclolysin (2)
    CCL8/MCP-2 (1)
    GFRAL (1)
    IL6 (2)
    VSIR/VISTA & CD274/PD-L1 (1)
    APP/Amyloid beta (1)
    HTRA1/PRSS11 (1)
    TIGIT (3)
    IL1A/IL1F1 (1)
    Spike glycoprotein 2 (5)
    ROBO2 (1)
    THPO/Thrombopoietin (1)
    APOE (1)
    CD228/MELTF (1)
    ADGRE1/F4/80 & CD3E (1)
    CD9 (1)
    TNFa/TNF-alpha (2)
    CD274/PD-L1 & CD3E (1)
    IGF2 (1)
    ADAMTS4 (4)
    F2/Prothrombin/PIVKA-II (1)
    CD268/TNFRSF13C (2)
    CD314/KLRK1 & CD3E (1)
    PDGFD (1)
    CD279/PD-1 (8)
    TPSAB1/Tryptase-1 (1)
    IL21 (1)
    CD276/B7-H3 & CD3E (1)
    CX3CL1/Fractalkine (1)
    LRRC15/LIB (1)
    IFNA1/Interferon alpha-D (1)
    CCL17/TARC (1)
    CD274/PD-L1 (5)
    ProteinUL128 & UL131A (1)
    gB/UL27 (1)
    IL11RA (2)
    L3/CP-H/Protein II (1)
    IL23A (1)
    HHRF3/US28 (1)
    Procapsid [(VP0/1/3) 5] 12 (2)
    F9/Factor IX (1)
    NP/Nucleoprotein (3)
    CD200 & CD47/MER6 (1)
    VEGFA (1)
    Spike glycoprotein (1)
    Protein prM/prM (3)
    S2/Spike protein S2' (1)
    BMP2 (1)
    Galectin-3/Gal-3 (1)
    P domain (1)
    EPOR (3)
    TERM2 (1)
    CD274/PD-L1 & CD47/MER6 (1)
    PDGFB (1)
    CDH11 (1)
    CSF3/G-CSF (1)
    Toxin A/tcdA (1)
    BMP6 (1)
    pro-MSTN/GDF8 (1)
    CD37/TSPAN26 (1)
    CD132/IL2RG (1)
    TGFB2/TGF-beta-2 (1)
    IFN α2/IFNA2 (1)
    CCL24/Eotaxin-2/MPIF-2 (1)
    Capsid protein VP25 (1)
    SSEA4 (4)
    gH/gL Complexes (2)
    CD79B & CD3E (1)
    SOST (1)
    IL36RN/IL-1F5/IL-36Ra (1)
    IL31 (4)
    KLKB1/KLK3 (1)
    env/Envpolyprotein (1)
    CXCL10/IP-10 (1)
    CD52 (1)
    CD295/LEPR (1)
    RBD (13)
    NS1 (1)
    CXCL12/SDF-1 (1)
    IL20 (1)
    HSP90 (1)
    GPA33 (1)
    HLA-A*11:01 (1)
    Intermediate capsid protein VP6 (1)
    Flt3 ligand/FLT3LG (1)
    GP1 glycoprotein (2)
    F/Fusion glycoprotein F0 (8)
    Capsid protein VP2 (1)
    ADAMTS5 (2)
    TRP-1 & CD3e (1)
    TGFA/TGF-alpha (1)
    CNR1/CB1 (3)
    HBEGF (1)
    iga/IgA1 protease (1)
    GDF2/BMP9 (1)
    WNT2 (2)
    mature virion in complex (5)
    gH/Envelope glycoprotein H (2)
    E1 & E2 (gp35 & gp70) (3)
    IL11 (2)
    NS1/Non-structural protein 1 (1)
    TGFB1 (2)
    TIGIT & CD274/PD-L1 (1)
    LRP6 (1)
    ACVRL1/ALK-1 & VEGFA (1)
    BMP10 (1)
    CD198/CCR8 (2)
    GP/Envelopment polyprotein (1)
    env/Env polyprotein (4)
    CD274/PD-L1 & CD134/OX40 (1)
    CD49d/ITGA4 (1)
    Fluorescein & CD3E (1)
    CD152/CTLA4 & CD274/PD-L1 (1)
    TRP-1 & CD47/MER6 (1)
    CDH1/CDH11 (1)
    CD20/MS4A1 (1)
    S1 N-terminal domain/S1-NTD (1)
    CA9 (1)
    FOLH1/PSMA (1)
    gD/Envelope glycoprotein D (2)
    F12/Coagulationfactor XII (1)
    CCL5/RANTES (1)
    RSPO3 (1)
    Fusion glycoprotein F0 (4)
    DPEP3 (1)
    GIPR/GIP-R (2)
    Glycoprotein G (6)
    gH/UL75 (1)
    MUC16/CA-125 (1)
    VWF (1)
    GPC (1)
    gB/Envelope glycoprotein B (8)
    ERBB3/HER3 (1)
    EPO (1)
    ApoC3 (1)
    ATTR/Transthyretin amyloidosis (4)
    L1/Major capsid protein L1 (2)
    Capsid protein (2)
    G/Major surface glycoprotein G (2)
    CD137/4-1BB (2)
    CD254/RANKL/TNFSF11 (1)
    L2/Minor capsid protein L2 (2)
    APCS/PTX2 (1)
    gp125 (1)
    CXCL11/I-TAC (1)
    CD99 (1)
    OSM/Oncostatin-M (1)
    ADM/Adrenomedullin (1)
    CD73/NT5E (2)
    CD40/TNFRSF5 (1)
    CXCL4/PF4 (1)
    CCL3/MIP-1-alpha (1)
    CCL11/Eotaxin (1)
    ENT2/SLC29A2 (1)
    CD152/CTLA4 (2)
    ANGPTL3 (1)
    RBD (S6P trimer) (3)
    IL17A (4)
    Tityustoxin VII/Toxin VII/Ts7 (1)
    NS1/gp68/gp70 (6)
    CD283/TLR3 (2)
    MASP2 (1)
    APOE4 (1)
    lukF (1)
    CD152/CTLA4 & CD134/OX40 (1)
    CD8a/Lyt2 (1)
    CSPG4/HMW-MAA/MCSP (1)
    PAUF (1)
    Major surface glycoprotein G (3)
    Pre-F/Fusion glycoprotein F0 (2)
    GPRC5D (1)
    TREM1 & CD46 (1)
    CD16/CD32 (1)
    shiga toxin type 2A/stx2A (1)
    EGFR/ERBB1 & CD3E (1)
    SOD1 (1)
    CCL1/I-309 (1)
    AFP/Alpha-fetoprotein (1)
    CTGF/CCN2 (1)
    Neuraminidase/NA (3)
    Fusion glycoprotein (4)
    CD274/PD-L1 & CD28 (1)
    PTP4A1/PRL1 (1)
    aPC/Activated protein C (3)
    FCGRT/FCRN (1)
    APOE3/4 (1)
    S-HBsAg/SHB (1)
    C1S (1)
    RBD (Omicron/JN.1) (2)
    FedF (1)
    IL12B/IL-12 p40 (1)
    Prefusion Protein (2)
    NA/Neuraminidase (1)
    BMP4 (1)
    gp120/Glycoprotein 120 (1)
    STEAP1 (1)
    TNFSF9/4-1BBL (2)
    Heparanase (1)
    CD16a/FCGR3A (3)
  • Species
    0 selected
    Sin Nombre virus (SNV) (2)
    Coxsackievirus B1 (CBV1) (3)
    Human endogenous retroviruses W (HERV-W) (1)
    Human papillomavirus 59 (HPV59) (1)
    Chikungunya virus (CHIKV) (1)
    Human (224)
    General (3)
    Plasmodium vivax (2)
    Epstein-Barr virus (EBV/HHV-4) (2)
    Poliovirus type 1 (PV1) (2)
    Plasmodium falciparum (2)
    Rotavirus A (RV-A) (4)
    Dengue virus type 2 (DENV-2) (9)
    Clostridium botulinum (2)
    Reston ebolavirus (REBOV) (1)
    Enterovirus D68 (EV-D68) (2)
    Junin mammarenavirus (JUNV) (1)
    Influenza A virus (Flu A) (9)
    Bordetella pertussis (2)
    Bundibugyo ebolavirus (BDBV) (1)
    Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) (21)
    Monkey (1)
    Mouse (65)
    Human herpesvirus 1 (HSV-1/HHV-1) (5)
    Suid alphaherpesvirus 1 (SuHV-1/PRV) (3)
    Dengue virus type 1 (DENV-1) (1)
    Human adenovirus 3 (HAdV-3) (1)
    Hantaan virus (HTNV) (2)
    Tai Forest ebolavirus (TAFV) (1)
    Hepatitis E virus/HEV (1)
    Ebola virus (EBOV) (1)
    Human cytomegalovirus (HCMV/HHV-5) (7)
    Enterovirus 71 (EV71) (4)
    Human astrovirus-8 (HAtVs) (1)
    Varicella-zoster virus (VZV/HHV-3) (4)
    Dog (11)
    Dengue virus type 3 (DENV-3) (1)
    Middle East respiratory syndrome-related coronavirus (MERS-CoV) (5)
    Zika virus (ZIKV) (2)
    Candida albicans (1)
    Cat (1)
    Machupo virus (MACV) (1)
    Human respiratory syncytial virus (HRSV) (14)
    Human hepatitis A virus (HHAV) (1)
    Puumala virus (PUUV) (2)
    Streptococcus pneumoniae (1)
    Coxsackievirus A16 (CVA16) (2)
    Human parvovirus B19 (HPV B19) (3)
    Orthohantavirus puumalaense (PUUV) (1)
    Sudan ebolavirus (SEBOV) (1)
    Nipah virus (NiV) (13)
    Dengue virus type 4 (DENV-4) (1)
    Lassa virus (LASV) (1)
    Dobrava-Belgrade virus (DOBV) (2)
    Human betacoronavirus 2c EMC/2012 (HCoV-EMC) (2)
    Human papillomavirus 6 (HPV6) (1)
    Porcine circovirus 2 (PCV2) (2)
    Bovine respiratory syncytial virus (BRSV) (2)
    Brazilian scorpion (1)
    Hepatitis C Virus (HCV) (9)
    Human papillomavirus 16 (HPV16) (2)
    Seoul virus (SEOV) (2)
    Human metapneumovirus (2)
    Rat (1)
    Human metapneumovirus (HMPV) (5)
    Rabbit (2)
    Staphylococcus aureus (3)
    Hepatitis B virus genotype A (HBV-A) (6)
    E. coli (4)
    Japanese encephalitis virus (JEV) (1)
    Human immunodeficiency virus 1 (HIV-1) (10)
    Zaire ebolavirus (ZEBOV) (6)
    Andes virus (ANDV) (2)
    Human papillomavirus 58 (HPV58) (3)
    Severe acute respiratory syndrome coronavirus (SARS-CoV) (3)
    Campylobacter jejuni subsp. (1)
    Rotavirus (RV) (1)
    Hendra virus (HeV) (2)
    Clostridioides difficile (2)
    Influenza B virus (Flu B) (1)
  • Applications
    0 selected
    in vivo CD4+ T cell depletion (1)
    in vivo PD-L1 blockade (3)
    Blocking (41)
    T cell depletion (Reported) (1)
    Agonist (8)
    in vitro PD-L1 blockade (3)
    Antagonist (1)
    FCM (77)
    IHC-F (3)
     ELISA (1)
    DB (2)
    in vivo research (1)
    WB (22)
    IF (8)
    SPR (18)
    Stimulatory (1)
    IP (5)
    IHC (6)
    RIA (1)
    FACS (2)
    Nneutralization (1)
    Cell Deplete (1)
    ELISA (424)
    ICC (1)
    in vivo blocking of PD-1/PD-L signaling (2)
    Functional assay (2)
    in vivo study (4)
    Neutralization (388)
    in vivo (1)
    T cell stimulation (Reported) (1)
    Research in vivo (2)
    FuncS (55)
  • Reactivity
    0 selected
    Mouse (12)
    Puumala virus (1)
    Human (16)
    Influenza B virus (1)
    Coxsackievirus B1 (CVB1) (3)
    Chikungunya virus (1)
  • Host species
    0 selected
    Hamster (1)
    Alpaca (5)
    Mouse (161)
    Dog (8)
    Cat (1)
    Human (319)
    Rat (11)
  • Clonality
    0 selected
    Monoclonal (510)
  • Conjugate
    0 selected
    Unconjugated (510)

Quick access

Contact Us

  • +86-027-65523339

  • info@abinscience.com

  • Building C, No. 666, Shen Dun Si Lu, Wuhan, 430206, China

Copyright © 2025 abinScience. All Rights Reserved. All Products are for Research Use Only