abinScience offers recombinant DENV antigens (E/EDIII, NS1, NS3, NS5, prM/M, C), validated antibodies, and RUO ELISA/neutralization tools. Each lot includes CoA with purity, endotoxin, linearity, and precision data. Flavivirus. RUO
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Selection guide
Antigen choice: Prioritize E/EDIII for neutralization/serology; use NS1 for early secreted antigen; select NS3/NS5 for enzymatic/mechanism studies; choose prM/M, C for assembly/maturation.
Serotype: Specify DENV-1/2/3/4; use conserved sites (e.g., parts of EDIII) or serotype-specific sequences to meet research goals.
Matrix & MRD: Follow CoA dilution and spiked recovery; evaluate matrix effects and background in serum/plasma.
Curve fitting: Use 4PL/5PL for ELISA; include negative/positive controls and L/M/H QC; report IC50/ID50 for neutralization.
What are the application differences between E/EDIII, NS1, and NS3/NS5?
E/EDIII: Core sites for antibody neutralization and serology; NS1: Secreted protein, often used in immunology/serology models; NS3/NS5: Key targets for enzymology and replication mechanism studies.
Can these products be used for diagnostics?
All products are for Research Use Only (RUO) and are not intended for diagnostic or therapeutic use.
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