Enterovirus 71 (EV71) Antigens & Antibodies

Research-grade reagents for Enterovirus 71 (EV71) — a picornavirus causing hand, foot, and mouth disease (HFMD) and severe neurological complications in children. VP1 is the key diagnostic and vaccine target, mediating viral attachment and tissue tropism. We offer recombinant/polyclonal/InVivoMAb antibodies, recombinant proteins, validated for ELISA, WB, IHC, FCM, IF, and neutralization assays. Comprehensive coverage of structural and non-structural proteins enables mechanistic studies of viral pathogenesis, immune response characterization, and vaccine antigen optimization. RUO

Why Researchers Choose abinScience

Recombinant Antibodies (5) Epitope-mapped clones for ELISA, Western blot, and immunoassay development. Suitable for diagnostic R&D and as reference standards for assay validation and quality control.

Polyclonal Antibodies (9) Broad epitope recognition for Western blot and immunohistochemistry detection. Validated for ELISA, WB, IHC, flow cytometry, immunofluorescence, and neutralization assays with high sensitivity and specificity.

InVivoMAb Functional-Grade (4) Low-endotoxin, azide-free antibodies for in vivo neutralization studies, passive immunization experiments, and functional blocking assays. Validated for protective immunity and viral clearance kinetics in animal models.

Recombinant Proteins (10) His-tagged and Fc-tagged antigens validated for SDS-PAGE, Western blot, and ELISA. Suitable as immunogens for antibody generation, coating antigens for serological assays, and assay standards for vaccine development.

All products manufactured by AtaGenix Laboratories under ISO 9001 & ISO 13485 quality systems.

References

1. Knowlton JL, Derrick SC, Yang SJ, et al. Enterovirus 71 VP1 vaccination elicits broadly cross-neutralizing antibodies. J Virol. 2012;86(12):6841-6844. DOI

2. Solomon T, Lewthwaite P, Perera D, et al. Management of suspected viral encephalitis in adults. J Infect. 2012;64(4):347-373. DOI

3. Cabezas C, Fiestas V, García W, et al. Molecular epidemiology of human enterovirus 71 in Peru. PLoS One. 2013;8(8):e71432. DOI

4. Tung WS, Bakar SA, Sekawi Z, Rosli R. Enterovirus 71: A review of epidemiology, virology, clinical presentations and treatment. Arch Virol. 2014;159(12):3393-3403. DOI