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Herpes Simplex Virus 1 (HSV-1)

abinScience offers recombinant HSV-1 antigens (gD, gB, gH/gL, gE/gI, VP5, ICP0/ICP4, Pol, TK), validated antibodies, and RUO ELISA/neutralization tools. Each lot includes CoA with purity, endotoxin, linearity, and precision data. Supports strain 17, KOS, F. Alphaherpesvirinae. RUO

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Selection guide

  1. Antigen choice: Prioritize gD for receptor binding (nectin-1/HVEM); gB for fusion; gH/gL for entry complex; gE/gI for immune evasion; ICP0/ICP4 for latency; Pol/TK for antiviral targets.
  2. Strain: Match to 17 (neurovirulence), KOS, or F (lab); use conserved domains for cross-reactivity.
  3. Expression: Mammalian (HEK293) for gD, gB, gH/gL to retain conformation/glycosylation; insect/bacterial for VP5, ICP, Pol with activity validation.
  4. Assay: Use plaque reduction (Vero) for neutralization; ELISA with 4PL/5PL; report IC50; validate with CoA MRD and recovery.

Spotlight

 

gD, Recombinant (HEK), Carrier-free

Purity ≥98% (SEC-HPLC) • Endotoxin ≤1 EU/µg • Nectin-1 binding confirmed

 

Anti-ICP0 (mAb), AF647 — WB/IF

High specificity • Low background • Matched controls

 

HSV-1 gD Neutralization Kit (RUO)

Functional titer • IC50 reporting • Reproducible PRNT

FAQs

What are gD, gB, gH/gL used for?

gD: Receptor engagement (nectin-1/HVEM). gB: Membrane fusion. gH/gL: Core fusion apparatus. gE/gI: Fc receptor mimicry, antibody evasion.

Which targets for antiviral drug screening?

UL30/Pol (DNA polymerase), UL23/TK (thymidine kinase), UL5/8/52 (helicase-primase) — validated for inhibitor binding and enzyme activity.

Can these be used in diagnostics?

All products are for Research Use Only (RUO) and not intended for diagnostic or therapeutic use.

36 product results for "Human Herpes Simplex Virus 1 (HSV-1)"

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