Bovine Viral Diarrhea Virus (BVDV) Reagents

Detect and characterize Bovine viral diarrhea virus (BVDV) — a pestivirus causing immunosuppression, reproductive failure, and mucosal disease in cattle with major economic impact on the livestock industry. Our portfolio covers the E2 envelope glycoprotein (the primary neutralizing antibody target and vaccine antigen), plus Erns, E1, NS3/p80, NS2/p54, NS4B, Capsid, and N-terminal protease (Npro) — with neutralizing recombinant antibodies, polyclonal detection antibodies, a recombinant nanobody, and His/Fc/GST-tagged recombinant proteins. RUO

E2 Glycoprotein — Antibodies & AntigensThe dominant target with 15 products. Recombinant antibody clones H15 and H18 validated for ELISA and neutralization. Polyclonal antibodies for ELISA, WB, and IHC. Recombinant E2 proteins available in His-tag, Fc-tag, and multiple construct variants — including a BVDV-2 genotype E2 for cross-genotype studies.

Structural & Non-Structural Protein PanelMatched polyclonal antibody + recombinant protein pairs for Erns/gp44/48, E1/gp33, NS3/p80, NS2/p54, NS4B, Capsid, and Npro. Each pair validated for ELISA, WB, and IHC — enabling multi-antigen BVDV profiling and differential diagnosis against other pestiviruses (CSFV, BDV).

Anti-NS4B Recombinant NanobodyVHH-based single-domain antibody (clone SAA2612) targeting BVDV NS4B, validated for ELISA, IF, and WB. Small format (~15 kDa) enables applications in immunofluorescence and intracellular staining where conventional IgG access is limited.

Recombinant Proteins (18)His-tagged, Fc-tagged, and GST-tagged BVDV antigens covering all major structural and non-structural proteins. Validated for SDS-PAGE, WB, ELISA, and as immunogens. Multiple tag and construct options per target for flexible assay configuration.

All products manufactured by AtaGenix Laboratories under ISO 9001 & ISO 13485 quality systems.

References

1. Walz PH, Chamorro MF, Falkenberg SM, et al. Bovine viral diarrhea virus: an updated American College of Veterinary Internal Medicine consensus statement. J Vet Intern Med. 2020;34(5):1690-1706. DOI

2. Tautz N, Tews BA, Meyers G. The molecular biology of pestiviruses. Adv Virus Res. 2015;93:47-160. DOI