Anti-CD85k/LILRB4/ILT3 Polyclonal Antibody (HV126014)

Name: Anti-CD85k/LILRB4/ILT3 Polyclonal Antibody
Brand: abinScience
SKU: HV126014
Price: 168 USD
Availability: InStock

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Overview
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References
Datasheet
SDS

Overview

Catalog No.

HV126014

Description

Anti-CD85k/LILRB4/ILT3 Polyclonal Antibody (HV126014) is a rabbit polyclonal antibody detecting LILRB4 in ELISA, IHC, WB. Suitable for Human.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Species reactivity

Human

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human CD85k/LILRB4 (Pro17-His257).

Target

CD85 antigen-like family member K, LIR-5, Leukocyte immunoglobulin-like receptor 5, ILT3, ILT-3, Immunoglobulin-like transcript 3, LILRB4, CD85k, Leukocyte immunoglobulin-like receptor subfamily B member 4, Monocyte inhibitory receptor HM18, LIR5

Purification

Purified by antigen affinity column.

Accession

Q8NHJ6

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Leukocyte immunoglobulin-like receptor subfamily B member 4 (CD85k/LILRB4) is a ~49 kDa protein. Inhibitory receptor involved in the down-regulation of the immune response and the development of immune tolerance. Receptor for FN1. Receptor for apolipoprotein APOE. Receptor for ALCAM/CD166. Inhibits receptor-mediated phosphorylation of cellular proteins and mobilization of intracellular calcium ions.

1. Chang, CC. et al. (2002) Nature immunology 3, 237-43. PMID: 11875462

2. Su, MT. et al. (2021) International immunology 33, 447-458. PMID: 34089617

3. Deng, M. et al. (2018) Nature 562, 605-609. PMID: 30333625

4. Xu, Z. et al. (2018) Journal of immunology (Baltimore, Md. : 1950) 200, 1207-1219. PMID: 29263213

5. Cella, M. et al. (1997) The Journal of experimental medicine 185, 1743-51. PMID: 9151699

6. Lu, HK. et al. (2009) The Journal of biological chemistry 284, 34839-48. PMID: 19833736

7. Kim-Schulze, S. et al. (2006) Journal of immunology (Baltimore, Md. : 1950) 176, 2790-8. PMID: 16493035

Note

For research use only.

Images

Western blot

Western blot analysis was performed using anti-CD85k/LILRB4/ILT3 polyclonal antibody at 1ug/mL on recombinant CD85k/LILRB4/ILT3 (Catalog No. HV126012).

References

Datasheet