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Anti-FGF13 Polyclonal Antibody (HV462014)

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Overview
Catalog No.HV462014
Description
Anti-FGF13 Polyclonal Antibody (HV462014) is a rabbit polyclonal antibody detecting FGF13 in ELISA, IHC, WB. Suitable for Human, Mouse, Rat, Pongo abelii, and Xenopus laevis.
Highlights
  • Affinity Purified — Minimal background and high purity for reliable results.
  • Multi-Application — Validated across multiple applications.
  • Multi-Species — Cross-reactive for translational research.
Species reactivityHuman, Mouse, Rat
ApplicationsELISA, IHC, WB
Host speciesRabbit
IsotypeIgG
Clonality Polyclonal
Immunogen E. coli - derived recombinant Human FGF13 (Gly108-Arg227).
Target FGF13, FHF-2, Fibroblast growth factor homologous factor 2, FGF-13, Fibroblast growth factor 13, FHF2
Purification Purified by antigen affinity column.
Accession Q92913
Form Liquid
Storage buffer 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information
Application Dilution
ELISA 1:5000-1:20000
IHC 1:50-1:500
WB 1:500-1:2000
Stability and Storage Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Background

Fibroblast growth factor 13 (FGF13) is a ~27 kDa protein. Microtubule-binding protein which directly binds tubulin and is involved in both polymerization and stabilization of microtubules. Through its action on microtubules, may participate in the refinement of axons by negatively regulating axonal and leading processes branching. Plays a crucial role in neuron polarization and migration in the cerebral cortex and the hippocampus. Regulates voltage-gated sodium channel transport and function. May also play a role in MAPK signaling.

1. Wittmack, EK. et al. (2004) The Journal of neuroscience : the official journal of the Society for Neuroscience 24, 6765-75. PMID: 15282281
2. Fry, AE. et al. (2021) American journal of human genetics 108, 176-185. PMID: 33245860
3. Fan, X. et al. (2023) Proceedings of the National Academy of Sciences of the United States of America 120, e2220578120. PMID: 36696443
Note For research use only.
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Formula
Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)
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Formula
C₁ × V₁ = C₂ × V₂
Enter any 3 of the 4 values to solve for the unknown.
Stock Solution
C₁ (Stock Conc.)
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V₁ (Stock Vol.)
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Working Solution
C₂ (Working Conc.)
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V₂ (Working Vol.)
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