

| Catalog No. | HV516014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-MGLL Polyclonal Antibody (HV516014) is a rabbit polyclonal antibody detecting MGLL in ELISA, IHC, WB. Suitable for Human.
Highlights
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| Species reactivity | Human | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Isotype | IgG | ||||||||
| Clonality | Polyclonal | ||||||||
| Immunogen | E. coli - derived recombinant Human MGLL (Met1-Pro303). | ||||||||
| Target | Lysophospholipase-like, MGLL, Monoacylglycerol lipase, Lysophospholipase homolog, MGL, Monoglyceride lipase, HU-K5, MAGL | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | Q99685 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Background | Monoglyceride lipase (MGLL) is a ~33 kDa protein. Converts monoacylglycerides to free fatty acids and glycerol. Hydrolyzes the endocannabinoid 2-arachidonoylglycerol, and thereby contributes to the regulation of endocannabinoid signaling, nociperception and perception of pain. Regulates the levels of fatty acids that serve as signaling molecules and promote cancer cell migration, invasion and tumor growth. 1. Long, JZ. et al. (2009) Nature chemical biology 5, 37-44. PMID: 19029917 2. Nomura, DK. et al. (2010) Cell 140, 49-61. PMID: 20079333 3. Xie, S. et al. (2010) Chemical research in toxicology 23, 1890-904. PMID: 21049984 4. Navia-Paldanius, D. et al. (2012) Journal of lipid research 53, 2413-24. PMID: 22969151 5. Laitinen, T. et al. (2014) Molecular pharmacology 85, 510-9. PMID: 24368842 | ||||||||
| Note | For research use only. |
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