Anti-CILK1 Polyclonal Antibody (HV486014)

Name: Anti-CILK1 Polyclonal Antibody
Brand: abinScience
SKU: HV486014
Price: 168 USD
Availability: InStock

Datasheet Share product Copy info

Price(USD):

Spec:

50ug
100ug

Number:

Get quote

Overview
Images
References
Datasheet
SDS

Overview

Catalog No.

HV486014

Description

Anti-CILK1 Polyclonal Antibody (HV486014) is a rabbit polyclonal antibody detecting CILK1 in ELISA, IHC, WB. Suitable for Human, Mouse, and Rat.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.
●Multi-Species — Cross-reactive for translational research.

Species reactivity

Human, Mouse, Rat

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human CILK1 (Met1-Gln277).

Target

Ciliogenesis associated kinase 1, Serine/threonine-protein kinase ICK, MAK-related kinase, ICK, KIAA0936, hICK, Laryngeal cancer kinase 2, CILK1, MRK, LCK2, Intestinal cell kinase

Purification

Purified by antigen affinity column.

Accession

Q9UPZ9

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Serine/threonine-protein kinase ICK (CILK1) is a ~71 kDa protein. Required for ciliogenesis. Phosphorylates KIF3A. Involved in the control of ciliary length. Regulates the ciliary localization of SHH pathway components as well as the localization of IFT components at ciliary tips. May play a key role in the development of multiple organ systems and particularly in cardiac development.

1. Chaya, T. et al. (2014) The EMBO journal 33, 1227-42. PMID: 24797473

2. Moon, H. et al. (2014) Proceedings of the National Academy of Sciences of the United States of America 111, 8541-6. PMID: 24853502

Note

For research use only.

Images

References

Datasheet

Anti-CILK1 Polyclonal Antibody.pdf

Download SDS PDF

Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-CILK1 Polyclonal Antibody (HV486014)

Overview

Images

References

Datasheet

SDS

Quick access

Contact Us