Anti-RAD54L2 Polyclonal Antibody (HV665014)

Name: Anti-RAD54L2 Polyclonal Antibody
Brand: abinScience
SKU: HV665014
Price: 96 USD
Availability: InStock

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Overview
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References
Datasheet
SDS

Overview

Catalog No.

HV665014

Description

Anti-RAD54L2 Polyclonal Antibody (HV665014) is a rabbit polyclonal antibody detecting RAD54L2 in ELISA, IHC, WB. Suitable for Human and Mouse.

Highlights

●Affinity Purified — Minimal background and high purity for reliable results.
●Multi-Application — Validated across multiple applications.

Species reactivity

Human, Mouse

Applications

ELISA, IHC, WB

Host species

Rabbit

Isotype

IgG

Clonality

Polyclonal

Immunogen

E. coli - derived recombinant Human RAD54L2 (Ala638-Ser837).

Target

Androgen receptor-interacting protein 4, KIAA0809, Helicase ARIP4, ARIP4, RAD54L2, RAD54-like protein 2

Purification

Purified by antigen affinity column.

Accession

Q9Y4B4

Form

Liquid

Storage buffer

0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

Product Usage Information

Application	Dilution
ELISA	1:5000-1:20000
IHC	1:50-1:500
WB	1:500-1:2000

Stability and Storage

Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.

Background

Helicase ARIP4 (RAD54L2) is a ~162 kDa protein. Helicase that modulates androgen receptor (AR)-dependent transactivation in a promoter-dependent manner. May stimulate the release of RNA polymerase II, that has paused near the transcription start sites of AR-targeted genes and unwind R-loops formed at these sites; R-loops result from the hybridization of the short RNA strand nascently synthesized by the paused RNA polymerase II molecule and the DNA template. May also stimulate double-strand break formation by TOP2B, which appears important for transcriptional output. Not able to remodel mononucleosomes in vitro.

1. Ng, RR. et al. (2024) Science advances 10, eadm9577. PMID: 39028815

Note

For research use only.

Images

References

Datasheet

Anti-RAD54L2 Polyclonal Antibody.pdf

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Formula

Mass (g) = Concentration (mol/L) × Volume (L) × MW (g/mol)

Enter any 2 of Mass, Concentration, Volume + Molecular Weight to solve for the unknown.

Mass

Concentration

Volume

Molecular Weight *

g/mol

Formula

C₁ × V₁ = C₂ × V₂

Enter any 3 of the 4 values to solve for the unknown.

Stock Solution

C₁ (Stock Conc.)

V₁ (Stock Vol.)

Working Solution

C₂ (Working Conc.)

V₂ (Working Vol.)

Recombinant Proteins

Antibodies

Assay Kits

Anti-RAD54L2 Polyclonal Antibody (HV665014)

Overview

Images

References

Datasheet

SDS

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