

| Catalog No. | HY151014 | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Description |
Anti-PPBP/CXCL7/NAP-2 Polyclonal Antibody (HY151014) is a rabbit polyclonal antibody detecting NAP-2 in ELISA, IHC, WB. Suitable for Human.
Highlights
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| Species reactivity | Human | ||||||||
| Applications | ELISA, IHC, WB | ||||||||
| Host species | Rabbit | ||||||||
| Isotype | IgG | ||||||||
| Clonality | Polyclonal | ||||||||
| Immunogen | E. coli - derived recombinant Human PPBP/CXCL7/NAP-2 (Ala59-Asp128). | ||||||||
| Target | NAP-2, NAP-2(1-63), NAP-2(73), PPBP, CXCL7, PBP, Small-inducible cytokine B7, Macrophage-derived growth factor, LA-PF4, Leukocyte-derived growth factor, CTAP-III, CTAP-III(1-81), Low-affinity platelet factor IV, TGB1, Beta-TG, C-X-C motif chemokine 7, MDGF, Platelet basic protein, LDGF, NAP-2(74), THBGB1, NAP-2(1-66), CTAP3, SCYB7 | ||||||||
| Purification | Purified by antigen affinity column. | ||||||||
| Accession | P02775 | ||||||||
| Form | Liquid | ||||||||
| Storage buffer | 0.01M PBS, pH 7.4, 50% Glycerol, 0.05% Proclin 300. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
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| Product Usage Information |
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| Stability and Storage | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. | ||||||||
| Background | Platelet basic protein (PPBP/CXCL7) is a ~13 kDa protein. LA-PF4 stimulates DNA synthesis, mitosis, glycolysis, intracellular cAMP accumulation, prostaglandin E2 secretion, and synthesis of hyaluronic acid and sulfated glycosaminoglycan. It also stimulates the formation and secretion of plasminogen activator by human synovial cells. NAP-2 is a ligand for CXCR1 and CXCR2, and NAP-2, NAP-2(73), NAP-2(74), NAP-2(1-66), and most potent NAP-2(1-63) are chemoattractants and activators for neutrophils. TC-1 and TC-2 are antibacterial proteins, in vitro released from activated platelet alpha-granules. CTAP-III(1-81) is more potent than CTAP-III desensitize chemokine-induced neutrophil activation. | ||||||||
| Note | For research use only. |

Western blot analysis was performed using anti-PPBP/CXCL7/NAP-2 polyclonal antibody at 1ug/mL on recombinant PPBP/CXCL7/NAP-2 (Catalog No. HY151012).




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